Business
Passage Bio Reports Third Quarter 2022 Financial Results and Provides Business Updates
Dosed first patient in final cohort, Cohort 4, in dose-ascending phase of Imagine-1 clinical trial for GM1 gangliosidosis; expect to dose the final patient in
About this update from Passage Bio, Inc.
[{"type":"text","content":"Dosed first patient in final cohort, Cohort 4, in dose-ascending phase of Imagine-1 clinical trial for GM1 gangliosidosis; expect to dose the final patient in this phase of the trial by year-endPlan to report initial safety and biomarker data from Cohorts 2 and 3 of Imagine-1 trial in December 2022Dosed first patient in Cohort 1 of upliFT-D clinical trial for frontotemporal dementiaCompany to streamline operations and refocus strategy, advancing Imagine-1 clinical trial for GM1 gangliosidosis,upliFT-D clinical trial for frontotemporal dementia and preclinical pipeline in adult CNS indicationsCash runway extended into 1H 2025 Management to host conference call today at 8:30 a.m. ET PHILADELPHIA, Nov. 10, 2022 (GLOBE NEWSWIRE) -- Passage Bio, Inc. (Nasdaq: PASG), a clinical-stage genetic medicines company focused on developing transformative therapies for central nervous system (CNS) disorders, today provided business updates and reported financial results for the third quarter ended September 30, 2022. “Passage Bio has tremendous potential to transform the lives of patients with devastating CNS orders for which there is significant unmet clinical need,” said William Chou, M.D., chief executive officer of Passage Bio. “To achieve this mission, we must be thoughtful in our allocation of resources to ensure we can deliver meaningful clinical data across our programs and maintain a best-in-class pipeline.” “Moving forward, we are streamlining our operations and refocusing our efforts to advance our ongoing Imagine-1 and upliFT-D clinical trials, providing opportunity to demonstrate proof of concept across both pediatric and adult CNS indications, and continue to advance our preclinical programs through our partnership with Penn’s Gene Therapy Program,” Dr. Chou added. “As we realign our organization around this more focused strategy, we would like to thank the talented team at Passage, particularly those who are impacted by today’s announcement, for their commitment to the pursuit of our ambitious mission.” Recent Business Updates Dosed first patient in final cohort, Cohort 4 (early infantile, high dose), in dose-ascending phase of Imagine-1 clinical trial: Dosing of the final patient in Cohort 4 is expected by year-end. The company plans to host a webcast to report interim safety and biomarker data from Cohorts 2 (late infantile, hi...