Business
Passage Bio Reports Third Quarter 2021 Financial Results and Provides Recent Business Highlights
On track to report initial safety and 30-day biomarker data for cohort 1 from Imagine-1 global Phase 1/2 trial for PBGM01 for the treatment of infantile GM1
About this update from Passage Bio, Inc.
[{"type":"text","content":"On track to report initial safety and 30-day biomarker data for cohort 1 from Imagine-1 global Phase 1/2 trial for PBGM01 for the treatment of infantile GM1 in 4Q21Activated multiple clinical sites across three global clinical programs, despite Covid-19 headwinds Expect to dose first participants in global Phase 1/2 trials for PBFT02 and PBKR03 in 4Q21Appointed Maxine Gowen, Ph.D., as chairwoman of the board of directorsManagement to host conference call today at 8:30 a.m. ET PHILADELPHIA, Nov. 04, 2021 (GLOBE NEWSWIRE) -- Passage Bio, Inc. (Nasdaq: PASG), a clinical-stage genetic medicines company focused on developing transformative therapies for central nervous system disorders, today reported financial results for the third quarter ended September 30, 2021 and provided recent business highlights. “We ended the quarter well-positioned to deliver on multiple upcoming catalysts, including reporting first-in-human data from our Imagine-1 global Phase 1/2 trial for PBGM01 for the treatment of infantile GM1 gangliosidosis before the end of year,” said Bruce Goldsmith, Ph.D., president and chief executive officer of Passage Bio. “We also have successfully activated multiple clinical sites and are continuously expanding our patient identification initiatives across each of our global clinical programs. This paves the way for us to continue to advance Imagine-1 and dose the first participants before year-end in our programs for Krabbe disease and frontotemporal dementia with granulin mutations. “As we close this year, we remain steadfastly focused on strong execution of our three clinical programs. Following the recent expansion of our strategic collaboration with University of Pennsylvania’s Gene Therapy Program, we also continue to progress our robust genetic medicines pipeline targeting CNS disorders affecting both rare and large patient populations.” Recent Highlights: Advancing Imagine-1 global Phase 1/2 trial toward data readout for cohort one in fourth quarter of 2021: Data will include initial safety and 30-day biomarker data, specifically beta-galactosidase enzyme activity levels in serum and cerebrospinal fluid. The company also plans to disclose the Independent Data Monitoring Committee recommendation on progressing to the higher-dose late infantile and low-dose early infantile GM1 patient cohorts.Activated multiple clinic...