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Palvella Therapeutics Strengthens QTORIN™ Pitavastatin Intellectual Property with Yale-Licensed U.S. Patent Providing Protection into 2043
Palvella Therapeutics Strengthens QTORIN™ Pitavastatin Intellectual Property with Yale-Licensed U.S. Patent Providing Protection into 2043
About this update from Palvella Therapeutics, Inc.
[{"type":"text","content":"Yale-licensed U.S. patent provides broad protection for topical mevalonate pathway inhibition in porokeratosis, including disseminated superficial actinic porokeratosis (DSAP) DSAP is a serious, rare, premalignant genetic skin disease affecting an estimated more than 50,000 diagnosed patients in the U.S., with no FDA-approved therapies Palvella plans to initiate a Phase 2 clinical trial of QTORIN™ pitavastatin in DSAP in the second half of 2026 WAYNE, Pa., May 27, 2026 (GLOBE NEWSWIRE) -- Palvella Therapeutics, Inc. (Palvella or the “Company”) (Nasdaq: PVLA), a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare skin diseases and vascular malformations for which there are no U.S. Food and Drug Administration (FDA)-approved therapies, today announced the issuance of U.S. Patent No. 12,636,273 by the United States Patent and Trademark Office. The issued patent, exclusively licensed by Palvella from Yale University, supports the Company’s QTORIN™ pitavastatin program for porokeratosis, including disseminated superficial actinic porokeratosis (DSAP). “This issued patent strengthens the IP position supporting QTORIN™ pitavastatin and represents an important step in advancing our pathogenesis-directed approach to porokeratosis,” said Wes Kaupinen, Founder and Chief Executive Officer of Palvella Therapeutics. “QTORIN™ pitavastatin is designed to combine a potent, next-generation statin with Palvella’s QTORIN™ platform to enable pathogenesis-directed inhibition of the mevalonate pathway on-target and directly within DSAP-affected tissue. We believe QTORIN™ pitavastatin has the potential to become a first-in-disease therapy for DSAP, a serious, rare, premalignant genetic skin disease affecting an estimated more than 50,000 diagnosed patients in the U.S., with no FDA-approved therapies.” The issued patent, exclusively licensed from Yale University, strengthens Palvella’s intellectual property position supporting QTORIN™ pitavastatin for porokeratosis, including DSAP. Building on pioneering work by Keith Choate, M.D., Ph.D., Chair and Professor of Dermatology, Pathology, and Genetics at Yale School of Medicine, the issued claims cover topical administration of HMG-CoA reductase inhibitors, including pitavastatin, for the treatment of porokeratosis...