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Palisade Bio Receives Canadian Patent Covering Composition of Lead Program in Development, LB1148

Carlsbad, CA, April 06, 2023 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (the “Company”), a biopharmaceutical company advancing therapies for acute

articlePalisade Bio, Inc.April 6, 20235/company/palisade-bio-inc/news/palisade-bio-receives-canadian-patent-covering-composition-of-lead-program-in-development-lb1148
Palisade Bio Receives Canadian Patent Covering Composition of Lead Program in Development, LB1148

About this update from Palisade Bio, Inc.

[{"type":"text","content":"Carlsbad, CA, April 06, 2023 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (the “Company”), a biopharmaceutical company advancing therapies for acute and chronic gastrointestinal (GI) complications, today announced that the Canadian Intellectual Property Office (CIPO) has issued Canadian Patent No. 2,942,358 titled, “Compositions for the Treatment of Autodigestion.” This key patent covers the composition of LB1148, the Company’s broad-spectrum serine protease inhibitor that acts to neutralize digestive enzymes, potentially reducing intestinal damage, until 2035. “As we continue to execute on our development path forward for LB1148, strengthening the intellectual property portfolio around this asset remains a priority. We are pleased to receive this Patent, which further bolsters our growing IP estate for LB114,” commented J.D. Finley, interim Chief Executive Officer of Palisade Bio. The allowed patent claims cover the proprietary composition LB1148. In clinical studies, LB1148 has demonstrated promising results in reducing the incidence and severity of post-surgical abdominal adhesions. LB1148 is currently being evaluated in a Phase 2 study for its effectiveness in reducing intra-abdominal adhesions, accelerating return of gastrointestinal function, and the prevention of post-operative ileus in subjects undergoing elective bowel resection (PROFILE). Palisade expects to report topline data from the 35 patients enrolled in the study in the second quarter of 2023. About Palisade Bio Palisade Bio is a biopharmaceutical company focused on developing therapeutics that protect the integrity of the intestinal barrier. The Company utilizes over three decades of research and established science that links the role of intestinal barrier biology and human disease to develop novel therapeutics that target and improve the integrity of the intestinal barrier. The Company’s lead program, LB1148, is a broad-spectrum serine protease inhibitor that acts to neutralize digestive enzymes, potentially reducing intestinal damage. In clinical studies, LB1148 has demonstrated positive results in reducing the incidence and severity of post-surgical abdominal adhesions and potentially accelerating the time to return of postoperative bowel function. LB1148’s current Phase 2 study is evaluating its effectiveness in reducing intra-abdominal adhesions,...

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