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Findings from Published Abstracts Showcase the Importance of Nicotinamide Adenine Dinucleotide (NAD+) in Glaucoma Patients and that Supplementation with Nicotinamide Riboside (NR) Demonstrate Promising Effects
Abstracts recently published in the Association for Research in Vision and Ophthalmology (ARVO) journal showcase NR, one of the most efficient and
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[{"type":"text","content":"\nAbstracts recently published in the Association for Research in Vision and Ophthalmology (ARVO) journal showcase NR, one of the most efficient and well-researched NAD+ precursors, prevented the worsening of visual field sensitivity in glaucoma patients, and builds on research demonstrating decreased cellular NAD+ levels and impaired mitochondrial function are associated with Primary open-angle glaucoma (POAG)\n\n\n LOS ANGELES--(BUSINESS WIRE)--\nChromaDex Corp. (NASDAQ:CDXC), the global authority on nicotinamide adenine dinucleotide (NAD+), announced promising findings from two independent clinical study abstracts originally presented this past April at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting and recently published in the peer-reviewed ARVO journal, Investigative Ophthalmology & Visual Science, by a team of scientists led by Dr. Christopher Leung from the Department of Ophthalmology at the School of Clinical Medicine, HKUMed, Hong Kong, and Dr. David F Garway-Heath, Professor of Ophthalmology at the UCL Institute of Ophthalmology and Moorfields Eye Hospital, London. Together, the promising results from these abstracts suggest that glaucoma patients have lower cellular NAD+ levels and thus replenishing NAD+ levels with a precursor, such as nicotinamide riboside (NR), may be a potential therapeutic strategy.\n\n\nDr. Garway-Heath’s abstract titled “Primary open angle glaucoma patients have lower systemic mitochondrial function, associated with lower systemic nicotinamide adenine dinucleotide (NAD) levels, compared to Controls” observed significantly lower cellular NAD+ levels and impaired mitochondrial function in patients with primary open-angle glaucoma (POAG). Further, higher NAD+ levels were strongly associated with higher mitochondrial function parameters, suggesting increased NAD+ levels are associated with improved energy production and cellular activity. POAG is a condition where pressure builds inside the eye, causing damage to the optic nerve and gradual vision loss. Unlike other types of glaucoma, most noticeable symptoms occur within advanced stages.\n\n\nThis research is consistent with research from a study led by Dr. Christopher Leung, which includes preliminary data from a clinical study set to complete in 2024, titled “Nicotinamide Riboside for Progressing Glaucoma: A Doub...