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ChromaDex Announces Issuance of New U.S. Patent on Dihydronicotinamide Riboside (NRH) and Dihydronicotinic Acid Riboside (NARH), Further Solidifying ChromaDex as the Leader in the Nicotinamide Adenine Dinucleotide (NAD+) Precursor Space
Preclinical research suggests that NRH may be among the most potent and efficient of NAD+ precursors, and shows promise as a new therapeutic approach to
About this update from Niagen Bioscience, Inc.
[{"type":"text","content":"\nPreclinical research suggests that NRH may be among the most potent and efficient of NAD+ precursors, and shows promise as a new therapeutic approach to ameliorating age-related NAD+ decline\n\n LOS ANGELES--(BUSINESS WIRE)--\nChromaDex Corp. (NASDAQ:CDXC), a global bioscience company dedicated to healthy aging, holds an exclusive license from Queen’s University Belfast for methods of making nicotinamide riboside (NR) and related derivatives, some of the most efficient nicotinamide adenine dinucleotide (NAD+) precursors, and today announced it expanded this patent family with newly granted U.S. Patent 11,584,770 for purity compositions of dihydronicotinamide riboside (NRH) and dihydronicotinic acid riboside (NARH). ChromaDex is continuously evaluating and investigating potential next generation NAD+ precursors, which are molecules at the forefront of the burgeoning healthy aging category, and currently owns and licenses a robust and secure portfolio of over 60 patents relating to Niagen® (patented NR) and other NAD+ precursors. Niagen® is the sole active ingredient in ChromaDex’s flagship consumer product, Tru Niagen®, the most efficient and well-studied NAD+ precursor currently in the market. These newly granted composition claims cover the commercially viable form of NRH and NARH, allowing ChromaDex to launch future innovations, and further strengthens ChromaDex’s position as the leading NAD+ company.\n\n“There is a great deal of interest in the scientific community around NRH,” said Rob Fried, CEO of ChromaDex. “Early studies have shown impressive results as a powerful NAD+ precursor. This patent covers food, dietary supplement and pharmaceutical applications.”\n\nNRH has gained considerable attention among NAD+ investigators as preclinical research suggests it is a more efficient and potent inducer of NAD+ over other precursors, and thus may be the most promising NAD+ precursor available (Molecular Metabolism, Journal of Biological Chemistry). Additionally, a new study conducted by Mayo Clinic suggests that NRH has the potential to promote the inflammatory response in macrophages, white blood cells that seek out and destroy microorganisms, remove dead cells, and stimulate the action of other immune system cells, indicating that NRH may be an important tool to understand the role of NAD+ and NADH metabolism in the immune re...