Neurocrine Biosciences Presents INGREZZA® (valbenazine) Capsules Data on Long-Term Improvements and Psychiatric Stability in Patients With Tardive Dyskinesia and Schizophrenia or Schizoaffective Disorder at the Schizophrenia International Research Soc...

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[{"type":"text","content":"Neurocrine Biosciences Presents INGREZZA® (valbenazine) Capsules Data on Long-Term Improvements and Psychiatric Stability in Patients With Tardive Dyskinesia and Schizophrenia or Schizoaffective Disorder at the Schizophrenia International Research Society 2023 Annual Congress \n \n\nSAN DIEGO, May 15, 2023 /PRNewswire/ -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX) today announced findings from a post hoc analysis of two long-term studies (KINECT™ 3 and KINECT™ 4) of INGREZZA® (valbenazine) capsules evaluating global tardive dyskinesia (TD) improvement and stability of psychiatric symptoms in adults with TD and schizophrenia or schizoaffective disorder. The data (Poster #SA135) was presented at the Schizophrenia International Research Society (SIRS) 2023 Annual Congress in Toronto, Canada.\n\n \n \n \n \n \n \n\n \nThe post hoc analysis found that patients with TD and schizophrenia or schizoaffective disorder who received long-term (48-week) treatment with once-daily INGREZZA (40 mg and 80 mg) while receiving concomitant, stable-dose medications for maintenance of their psychiatric condition experienced long-term global improvements in TD, with more than 90 percent of patients having a rating of \"minimally improved\" or better, and more than 75 percent of patients having a rating of \"much improved\" or better using the Clinical Global Impression of Change-Tardive Dyskinesia (CGI-TD) and Patient Global Impression of Change (PGIC), respectively. Importantly, patients maintained psychiatric stability throughout treatment with INGREZZA, as indicated by Positive and Negative Syndrome Scale (PANSS) and Calgary Depression Scale for Schizophrenia (CDSS) scores.\n\"It is important to consider all aspects of patient health when managing TD symptoms, especially underlying and often complex psychiatric conditions that may require multiple treatments,\" said Eiry W. Roberts, M.D., Chief Medical Officer at Neurocrine Biosciences. \"These data demonstrate that psychiatric stability can be maintained in patients living with schizophrenia or schizoaffective disorder while actively improving and managing TD symptoms with INGREZZA.\"\nKey results from the analysis demonstrated the following:\nMore than 90 percent of patients treated with INGREZZA had a clinician-reported (CGI-TD = 94.3 percent, n=116/123) or patient-reported (PGIC = 91.9 percent...

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