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Mineralys Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Corporate Update
– Lorundrostat pivotal clinical program, for the treatment of patients with uncontrolled hypertension, expected to begin in the first half of 2023 – –IPO and
About this update from Mineralys Therapeutics, Inc.
[{"type":"text","content":"– Lorundrostat pivotal clinical program, for the treatment of patients with uncontrolled hypertension, expected to begin in the first half of 2023 – –IPO and Nasdaq listing completed in February 2023 with total net proceeds of approximately $202.0 million, after deducting underwriting discounts, commissions and estimated offering costs – – Conference call today at 4:30 p.m. ET – RADNOR, Pa., March 15, 2023 (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a clinical-stage biopharmaceutical company focused on developing medicines to target diseases driven by abnormally elevated aldosterone, today announced financial results for the fourth quarter and full year ending December 31, 2022, and provided a corporate update. “I am extremely proud of the Mineralys Therapeutics team as we continue to make tremendous progress advancing the clinical development of lorundrostat – our proprietary highly selective aldosterone synthase inhibitor designed to reduce aldosterone levels – for the treatment of hypertension. This is a critical milestone in our Company’s history, as we prepare to initiate the pivotal program to evaluate the safety and efficacy of lorundrostat for the treatment of uncontrolled and resistant hypertension in the first half of 2023,” stated Jon Congleton, Chief Executive Officer of Mineralys Therapeutics. “Uncontrolled and resistant hypertension continue to impact individual patient’s lives and the healthcare system at large. The closing of our IPO in February enables us to continue our efforts of developing a targeted treatment approach for hypertension with lorundrostat.” Recent Corporate and Clinical Highlights Topline Data Target-HTN Phase 2 trial – In November 2022, the Company announced positive topline data from its Target-HTN trial, a Phase 2 proof-of-concept trial for lorundrostat in the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN), which support advancing the development of lorundrostat into the planned pivotal clinical program.FDA End of Phase 2 Meeting – In November 2022, the Company held an end of Phase 2 meeting with the U.S. Food and Drug Administration (FDA) to review the positive results of the Target-HTN trial, and to discuss the plans for a pivotal program for lorundrostat in hypertension. Based on the Phase 2 results and feedback from the FDA, the Compa...