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Synthekine Announces Clinical Trial Collaboration with Merck to Evaluate STK-012 In Combination with Keytruda® (Pembrolizumab) and Chemotherapy in Ongoing Randomized Phase 2 Trial in First-Line, PD-L1 Negative Nonsquamous Non-Small Cell Lung Cancer

MENLO PARK, Calif., February 26, 2026--Synthekine Inc., an engineered cytokine therapeutics company, today announced that it has entered into a clinical trial collaboration and supply agreement with Merck (known as MSD outside of the United States and Canada). STK-012, a first-in-class α/β-IL-2 receptor biased partial agonist, will be evaluated in combination with standard of care chemotherapy and Keytruda® (pembrolizumab), Merck’s anti-PD-1 (programmed cell death receptor-1) therapy, in the ong

articleMerck & Company, Inc.February 26, 20263/company/merck-and-company-inc/news/synthekine-announces-clinical-trial-collaboration-with-merck-to-evaluate-stk-012-in-combination-with-keytrudar-pembrolizumab-and-chemotherapy-in-ongoing-randomized-phase-2-trial-in-first-line-pd-l1-negative-nonsquamous-non-small-cell-lung-cancer
Synthekine Announces Clinical Trial Collaboration with Merck to Evaluate STK-012 In Combination with Keytruda® (Pembrolizumab) and Chemotherapy in Ongoing Randomized Phase 2 Trial in First-Line, PD-L1 Negative Nonsquamous Non-Small Cell Lung Cancer

About this update from Merck & Company, Inc.

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More updates from Merck & Company, Inc.

Synthekine IncMerckchemotherapyKeytrudapartial agoniststandard of careNSQ