Business

MediWound Announces Publication of Phase II EscharEx® Data Demonstrating Superiority Over Collagenase in Venous Leg Ulcers

Post hoc analysis published in the peer-reviewed journal Wounds highlights EscharEx®’s superior clinical performance and comparable safety profile to SANTYL®YAVNE, Israel, May 13, 2025 (GLOBE NEWSWIRE) -- MediWound Ltd. (Nasdaq: MDWD), a global leader in next-generation enzymatic therapeutics for tissue repair, today announced the publication of a peer-reviewed post hoc analysis in Wounds. The analysis is based on data from the Company’s Phase II ChronEx clinical trial in patients with venous le

articleMediwound Ltd.May 13, 20253/company/mediwound-ltd/news/mediwound-announces-publication-phase-ii-113000884
MediWound Announces Publication of Phase II EscharEx® Data Demonstrating Superiority Over Collagenase in Venous Leg Ulcers

About this update from Mediwound Ltd.

[{"type":"image","alt":"MediWound Ltd.","displaySize":"","headline":null,"caption":"MediWound Ltd.","className":"","disableSlideshowImg":false,"size":{"original":{"width":300,"height":113,"url":"https://media.zenfs.com/en/globenewswire.com/ad5b557425c9c98b1d6e3e31c57b3159"},"resized":{"url":"https://s.yimg.com/ny/api/res/1.2/lMBSATvDCuA9PnawJVvewQ--/YXBwaWQ9aGlnaGxhbmRlcjt3PTQyMDtoPTE1ODtjZj13ZWJw/https://media.zenfs.com/en/globenewswire.com/ad5b557425c9c98b1d6e3e31c57b3159","width":300,"height":113}},"lazy":false},{"type":"text","content":"Post hoc analysis published in the peer-reviewed journal Wounds highlights EscharEx®’s superior clinical performance and comparable safety profile to SANTYL®","length":157,"tagName":"p"},{"type":"text","content":"YAVNE, Israel, May 13, 2025 (GLOBE NEWSWIRE) -- MediWound Ltd. (Nasdaq: MDWD), a global leader in next-generation enzymatic therapeutics for tissue repair, today announced the publication of a peer-reviewed post hoc analysis in Wounds. The analysis is based on data from the Company’s Phase II ChronEx clinical trial in patients with venous leg ulcers (VLUs) evaluating the efficacy and safety of EscharEx® compared with collagenase ointment (SANTYL®), the only FDA-cleared enzymatic debridement agent commercially available for the treatment of dermal ulcers.","length":560,"tagName":"p"},{"type":"text","content":"The article, titled “Bromelain-Based Debridement Versus Collagenase Ointment Debridement of Venous Leg Ulcers: Post Hoc Analysis of the ChronEx Trial,” appears in the April 2025 edition of Wounds (Index 2025;37(4):166–173) and compares outcomes in a subgroup of patients from the non-surgical standard of care arm treated with SANTYL (n=8) to those treated with EscharEx (n=46).","length":378,"tagName":"p"},{"type":"text","content":"“These new findings are consistent with my prior experience using EscharEx in clinical trials and SANTYL in clinical practice,” said Dr. Cyaandi Dove, DPM, of the University of Texas Health Science Center at San Antonio and co-author of the publication. “Compared to SANTYL, EscharEx achieved faster and more effective debridement and promoted healthier granulation tissue, both key to optimal wound bed preparation. EscharEx’s enzymatic formulation targets a wider range of non-viable and necrotic tissue, which may account for the favorable clinical outcomes observed.”","length":571,"...

More updates from Mediwound Ltd.

MediWound Ltd.enzymatic debridementvenous leg ulcersgranulation tissuepost hoc analysisSANTYLWBPpatientstissue repair