Press release
New Study Investigates the Ability of Masimo ORi™ to Provide Early Warning of Hypoxemia During Endotracheal Intubation in ICU Patients
Researchers Found That Use of ORi May Facilitate “Preventive Action” Against Hypoxemia NEUCHATEL, Switzerland--(BUSINESS WIRE)-- Masimo (NASDAQ: MASI)
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[{"type":"text","content":"\nResearchers Found That Use of ORi May Facilitate “Preventive Action” Against Hypoxemia\n\n NEUCHATEL, Switzerland--(BUSINESS WIRE)--\nMasimo (NASDAQ: MASI) announced today the findings of a prospective, blinded observational study published in Annals of Intensive Care in which Dr. Jean-Baptiste Lascarrou and colleagues at the Centre Hospitalier Universitaire in Nantes, France evaluated the ability of Masimo ORi™ to predict mild hypoxemia during endotracheal intubation (ETI) in ICU patients.1 They concluded that the time between decrease in ORi and subsequent decrease in oxygen saturation (SpO2) “may allow preventive action,” and that a higher ORi value during preoxygenation was “independently protective against hypoxemia.”\nThis press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20210905005031/en/Masimo Root® with ORi™ (Photo: Business Wire)\nORi, available outside the U.S., is a noninvasive and continuous trending index that extends oxygen monitoring on patients on supplemental oxygen. Enabled by the multi-wavelength rainbow® Pulse CO-Oximetry platform, ORi is provided alongside oxygen saturation (SpO2) measured by clinically proven Masimo SET® pulse oximetry.\n\nNoting the importance of optimizing preoxygenation in patients needing ETI, the researchers sought to evaluate whether ORi could provide early warning of impending hypoxemia during the procedure, because ORi “supplies information beyond the range explored by SpO2.” Of the 51 patients who met the inclusion criteria, ORi (alongside SpO2) was monitored using Masimo Radical-7® Pulse CO-Oximeters® and rainbow® fingertip sensors when preoxygenation began. Values were recorded every two seconds, and attending clinicians were not aware of these values. The primary endpoint measured was the time between ORi decreasing below 0.4 and the onset of mild hypoxemia (defined as SpO2 \nAnalyzing areas under the ROC curve, the researchers found that ORi during preoxygenation predicted SpO2 \nThe researchers concluded, “The median time between the ORi decrease below 0.4 and the SpO2 decrease below 97% during the apneic period was 81 seconds [34–146]. A higher ORi during preoxygenation was independently associated with a lower risk of mild hypoxemia (SpO2 \nThe researchers noted that the median 81 seconds of forewarning “may allow immed...