Press release
New Study Evaluates the Use of Masimo PVi® As an Indicator of Fluid Responsiveness to Guide Goal-Directed Fluid Therapy in Elderly Patients Undergoing Gastrointestinal Surgery
Researchers Found That Fluid Therapy Guided by Noninvasive, Continuous PVi Reduced Cardiopulmonary Complications and Fluid Administered NEUCHATEL,
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[{"type":"text","content":"\nResearchers Found That Fluid Therapy Guided by Noninvasive, Continuous PVi Reduced Cardiopulmonary Complications and Fluid Administered\n\n\n NEUCHATEL, Switzerland--(BUSINESS WIRE)--\nMasimo (NASDAQ: MASI) today announced the findings of a prospective, randomized study published in Perioperative Medicine in which Dr. Yu Wang and colleagues at institutions in Shenzhen, Shaoguan, and Guangzhou, China evaluated the use of noninvasive, continuous Masimo PVi®, as part of goal-directed fluid therapy (GDFT), to guide intraoperative fluid administration during gastrointestinal (GI) surgery on elderly patients by comparing it to conventional fluid therapy. The researchers found that patients in the PVi group had a significantly lower rate of cardiopulmonary complications (8.4% vs 19.2%) and had a significantly lower total volume of fluid administered (median 2075 ml vs. 2500 ml).1\n\nThis press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20230820369137/en/Masimo Root® with PVi® and SpHb® (Photo: Business Wire)\nNoting the particular value of optimizing fluid management during GI procedures, especially in elderly patients, because of the high rate of postoperative complications and frequent fluid deficits (because of preoperative fasting, bowel preparation, and intraoperative fluid loss), the researchers sought to determine whether GDFT using Masimo PVi might improve outcomes in this challenging scenario. PVi, or pleth variability index, is a measure of the variations in perfusion index over the respiratory cycle, and has the advantage, compared to arterial line-based methods of gauging fluid responsiveness (e.g. stroke volume variation [SVV] and pulse pressure variation [PPV]), of being obtained via noninvasive Masimo rainbow SET® pulse oximetry and Pulse CO-Oximetry. PVi is indicated as a noninvasive, dynamic indicator of fluid responsiveness in select populations of mechanically ventilated adult patients. As the researchers note, PVi has been shown to perform similarly to invasive methods of fluid assessment, such as PPV and SVV, in a variety of surgeries.2\n\n\nThe researchers enrolled patients aged ≥ 65 years scheduled for elective GI surgery at two university hospitals between November 2017 and December 2020. Patients were randomly assigned to the GDFT group (n = 107) or the con...