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Cygnus Technologies Receives 2023 R&D 100 Award for MockV® RVLP Kit
LELAND, N.C., Aug. 23, 2023 (GLOBE NEWSWIRE) -- Cygnus Technologies, part of Maravai LifeSciences (Maravai) (NASDAQ: MRVI), the leading product and services
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[{"type":"text","content":"LELAND, N.C., Aug. 23, 2023 (GLOBE NEWSWIRE) -- Cygnus Technologies, part of Maravai LifeSciences (Maravai) (NASDAQ: MRVI), the leading product and services provider for the detection and characterization of process-related impurities in biopharmaceuticals, received a 2023 R&D 100 Award from R&D World Magazine in the Analytical/Test category for the MockV® RVLP Kit. The MockV® RVLP Kit enables bioprocess scientists to determine Retrovirus Like Particle (RVLP) removal during biopharmaceutical manufacturing in Chinese Hamster Ovary (CHO) cell lines. The kit includes a biosafety level-1 (BSL-1) compatible RVLP stock solution and all the necessary reagents to quantify RVLP removal using a 96-well plate assay in less than one day. “We are honored to be recognized among many innovative companies pushing the boundaries of what is possible in R&D,” said Christine Dolan, Cygnus Technologies Chief Operating Officer. “This award exemplifies our dedication to improving biopharmaceutical manufacturing safety with our accurate and reliable MockV® viral clearance technology. We thank the staff at R&D World and the esteemed judging panel for recognizing the ingenuity of product line inventor, David Cetlin, and his team at Cygnus.” “During the production of monoclonal antibody therapies, regulatory agencies require proof that downstream purification steps can effectively remove or inactivate retrovirus. Historically, this has been demonstrated through the use of a model mammalian virus, Xenotropic Murine Leukemia Virus (XMuLV), which requires high costs and specialized contract research organization (CRO)-led viral clearance “spiking” studies,” commented David Cetlin, Cygnus Technologies Senior Director of R&D. “Using the MockV® RVLP Kit, scientists can gain actionable insight into retroviral clearance whenever they wish, from their own lab bench, at a fraction of the costs associated with XMuLV studies.” Cygnus’s MockV® technology addresses the barriers imposed by live viral clearance studies through novel viral surrogates called Mock Viral Particles (MVPs). MVPs are engineered to mimic the physical and chemical characteristics of viruses but are non-infectious and can be handled safely and easily to predict the outcomes of CRO-led spiking studies early in process development. Cygnus’s MockV® RVLP Kit enables biopharmaceutical companies to deve...