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Lucid Diagnostics Releases Positive Data from First Prospective Clinical Utility Study of EsoGuard® Esophageal Precancer Detection
Multicenter observational study documents excellent concordance of EsoGuard results with subsequent medical decision-making by multiple physicians NEW YORK,
About this update from Lucid Diagnostics Inc.
[{"type":"text","content":"Multicenter observational study documents excellent concordance of EsoGuard results with subsequent medical decision-making by multiple physicians\nNEW YORK, Sept. 7, 2023 /PRNewswire/ -- Lucid Diagnostics Inc. (Nasdaq: LUCD) (\"Lucid\" or the \"Company\") a commercial-stage, cancer prevention medical diagnostics company, and majority-owned subsidiary of PAVmed Inc. (Nasdaq: PAVM, PAVMZ) ( \"PAVmed\"), today announced it has released positive interim data from the multicenter, CLinical Utility of EsoGuard (CLUE) study. This is the Company's first report of prospective data from multiple physicians demonstrating real-world clinical utility of EsoGuard® Esophageal DNA testing for the detection of esophageal precancer; and supplements its recently released positive data from a retrospective analysis of EsoGuard's clinical utility in firefighters.\n\n \n \n \n \n \n \n\n \nThe study documents near perfect concordance, including 100 percent concordance in EsoGuard-positive patients, between clinically-directed EsoGuard test results and subsequent medical decision-making by multiple different prescribing physicians. It demonstrates that EsoGuard allows physicians to appropriately triage those requiring confirmatory endoscopy in a manner broadly consistent with established, and recently updated, professional society guidelines. The manuscript entitled Clinical Utility Study of EsoGuard® on Samples Collected with EsoCheck® as a Triage Test for Endoscopy to Identify Barrett's Esophagus – Interim Data of the First 275 Subjects is available on the leading health sciences preprint server, medRxiv, pending peer review and publication.\n\"Prospective clinical utility data involving multiple physicians provides the strongest level of evidence to payors, and other stakeholders, that a diagnostic test such as EsoGuard has real-world clinical utility driving appropriate medical decision making,\" said Victoria T. Lee, M.D., PAVmed's Senior Vice President and Chief Medical Officer of PAVmed, who oversees all of Lucid's clinical research activities. \"We designed CLUE to demonstrate to payors that a diverse group of physicians across multiple centers will clinically utilize EsoGuard to appropriately refer at-risk patients with positive results for confirmatory endoscopy, and not refer those with negative results unless another indication for endosc...