Business
Longeveron Inc. Provides Corporate Update and Reports Third Quarter 2021 Financial Results
Longeveron to hold conference call today at 8:30 AM EST MIAMI, Nov. 12, 2021 (GLOBE NEWSWIRE) -- Longeveron Inc. (NASDAQ: LGVN) ("Longeveron" or "Company"), a
About this update from Longeveron Inc.
[{"type":"text","content":"Longeveron to hold conference call today at 8:30 AM EST\nMIAMI, Nov. 12, 2021 (GLOBE NEWSWIRE) -- Longeveron Inc. (NASDAQ: LGVN) (\"Longeveron\" or \"Company\"), a clinical stage biotechnology company developing cellular therapies for chronic aging-related and life-threatening conditions, today provided a business update regarding the status of the Company’s various clinical research programs and reported its financial results for the quarter ended September 30, 2021. “In the third quarter of 2021, we continued executing across our pipeline,” said Geoff Green, CEO of Longeveron. “With a growing base of encouraging clinical data, we continue to make excellent progress in advancing our lead candidate, Lomecel-B, into next phase trials. In addition to the ongoing Phase 1 and 2 trials in flu and COVID-related Acute Respiratory Distress Syndrome (ARDS), and Hypoplastic Left Heart Syndrome (HLHS), we anticipate initiating our Phase 2 Alzheimer’s disease and Japanese Phase 2 Aging Frailty studies by year end, or in the first quarter of 2022.” Business Update: Lomecel-B Clinical Research Developments: Hypoplastic Left Heart Syndrome: In July, Longeveron announced initiation of enrollment for the Phase 2 randomized, double-blind, controlled clinical trial evaluating Lomecel-B intraventricular injection in infants with HLHS (“ELPIS II” trial). With a target enrollment of 38 infants, the Company anticipates ELPIS II will enroll across several children’s hospitals in major metropolitan centers located throughout the United States. ELPIS II is being funded in part by a grant from the National Institute of Health’s National Heart, Lung, and Blood Institute (NHLBI; Grant number 1UG3HL148318). Aging Frailty: Longeveron previously announced in August the initial results of the Phase 2b U.S. Aging Frailty trial. Clinical safety and efficacy data continue to be evaluated, as well as the blood-based biomarker data, as the Company evaluates the next step in this research program. Results from Longeveron’s other Aging Frailty trial, the Phase 1/2 “HERA” study, are anticipated in the first quarter of 2022. The primary objectives of the HERA study are to assess safety and tolerability, and explore the effect of Lomecel-B on the frail immune system and other frailty endpoints, in subjects receiving the influenza vaccine.The planned Japanese Aging Frailt...