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Lexaria Provides Progress Report on Six R&D Programs

All studies are using DehydraTECH™ 2.0 formulations for multiple market applications, including antivirals, hypertension, NSAIDs and oral nicotineThese

articleLexaria Bioscience Corp.June 9, 20214/company/lexaria-bioscience-corp/news/lexaria-provides-progress-report-on-six-randd-programs
Lexaria Provides Progress Report on Six R&D Programs

About this update from Lexaria Bioscience Corp.

[{"type":"text","content":"All studies are using DehydraTECH™ 2.0 formulations for multiple market applications, including antivirals, hypertension, NSAIDs and oral nicotineThese studies are part of Lexaria's 2021 applied R&D program intended to enable opportunities for strategic partnershipsKELOWNA, BC / ACCESSWIRE / June 9, 2021 / Lexaria Bioscience Corp. (Nasdaq:LEXX) (Nasdaq:LEXXW) (CSE:LXX) (the \"Company\" or \"Lexaria\"), a global innovator in drug delivery platforms, provides this progress report on several studies within its 2021 applied research and development (R&D) program. Other studies actively underway and planned will be reported on separately.VIRAL-A20-2 - A tolerability and pharmacokinetic or \"PK\" study in animals using antiviral drugs remdesivir and ebastine.Animal dosing and all in-life procedures and sample analyses have been completed. Data analyses is underway with a view to reporting soon. There were 4 groups of 10 animals dosed to determine if DehydraTECH-enhanced remdesivir and ebastine were well tolerated and enabled improved overall quantity of drug delivery (\"Area Under the Curve\", or \"AUC\") relative to non-enhanced controls as Lexaria has successfully evidenced for other antiviral drugs. Lexaria hopes to build on recently announced positive findings from its VIRAL-C21-3 study that evidenced effective inhibition of the COVID-19 SARS-CoV-2 virus using these DehydraTECH-enhanced compounds in an in vitro screening assay.VIRAL-A20-3 - An additional tolerability and PK study in animals evaluating AUC for 3 other antiviral drugs.Animal dosing and all in-life procedures have been completed, and sample analyses is ongoing. There were 6 groups of 10 animals dosed in this study examining tolerability and quantity of drug delivery for 3 other antiviral drugs of interest with potential utility against the COVID-19 SARS-CoV-2 virus. This study is expected to generate reportable results during July or August.VIRAL-MC21-1 - A molecular characterization (\"MC\") study being performed by Canada's National Research Council.In this study, Nuclear Magnetic Resonance (\"NMR\") and Liquid Chromatography-High Resolution Mass Spectrometry (\"LC-HRMS\") are being applied to 5 DehydraTECH-enhanced antiviral drug formulations currently being investigated by the Company in studies VIRAL-A20-2 and VIRAL-A20-3. Molecular characterization is an import...

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