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Kymera Therapeutics Presents KT-621 BroADen Data in Late-Breaking Research Session at the American Academy of Dermatology (AAD) Annual Meeting
Featured presentation highlights positive BroADen Phase 1b atopic dermatitis trial results supporting KT-621’s compelling oral profile Parallel Phase 2b
About this update from Kymera Therapeutics, Inc.
[{"type":"text","content":"Featured presentation highlights positive BroADen Phase 1b atopic dermatitis trial results supporting KT-621’s compelling oral profile Parallel Phase 2b trials, BROADEN2 in atopic dermatitis and BREADTH in asthma, ongoing with data expected by mid-2027 and late-2027, respectively WATERTOWN, Mass., March 28, 2026 (GLOBE NEWSWIRE) -- Kymera Therapeutics, Inc. (NASDAQ: KYMR), a clinical-stage biopharmaceutical company advancing a new class of oral small molecule degrader medicines for immunological diseases, today announced that the positive results from the BroADen Phase 1b atopic dermatitis (AD) clinical trial of KT-621, its first-in-class, oral STAT6 degrader, were featured in a late-breaking oral presentation at the American Academy of Dermatology (AAD) Annual Meeting. The meeting is being held March 27-31, 2026, in Denver, CO. “We’re proud to share our compelling KT-621 Phase 1b results with the dermatology community at AAD. Our goal is to advance the standard of care for patients around the world, and we believe these findings bring us an important step closer to that objective,” said Jared Gollob, MD, Chief Medical Officer, Kymera Therapeutics. “People living with atopic dermatitis and other Type 2 inflammatory diseases are often forced to navigate difficult tradeoffs between efficacy, safety and convenience when choosing treatment. With our novel targeted protein degradation approach, we believe KT-621 has the potential to offer a first-in-class, once-daily oral option and open new possibilities for patients. These early data showing encouraging biological and clinical activity highlight the potential to expand treatment options and improve outcomes for those with chronic immuno-inflammatory conditions.” “Despite systemic therapy advances in recent years, only a fraction of patients with moderate to severe atopic dermatitis actually go onto these treatments due to access challenges or concerns related to chronic injections or safety,” said Emma Guttman-Yassky, MD, PhD, Waldman Professor of Dermatology and Immunology and Health System Chair of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai*. “Targeting the Type 2 inflammatory pathway through STAT6 degradation is an exciting mechanism. The early data showing impact on both biomarkers and clinical measures support furt...