Business
Krystal Biotech Reports 2019 Financial Results and Business Progress
Phase 3 trial of B-VEC (Beremagene Geperpavec, previously “KB103”) to treat dystrophic epidermolysis bullosa (“DEB”) to start in 1H 2020 Interim results on
About this update from Krystal Biotech, Inc.
[{"type":"text","content":"Phase 3 trial of B-VEC (Beremagene Geperpavec, previously “KB103”) to treat dystrophic epidermolysis bullosa (“DEB”) to start in 1H 2020\n Interim results on Phase 1/2 clinical study on KB105 to be announced in 1H 2020 Planned filing of two Investigational New Drug Applications (“INDs”), one for rare skin disease and another for an aesthetic skin indication, in 2H 2020 Company strengthens portfolio with four new patents covering B-VEC, KB105 and the STAR-D platform PITTSBURGH, March 10, 2020 (GLOBE NEWSWIRE) -- Krystal Biotech Inc., (“Krystal”) (NASDAQ: KRYS), a gene therapy company developing medicines to treat dermatological diseases, announces financial results for 2019 and an update on its business progress. Krish S. Krishnan, chairman and chief executive officer of Krystal Biotech stated, “2020 is expected to be an exciting year for Krystal as we get ready to commence the pivotal study of B-VEC, and announce interim Phase 1/2 clinical results on KB105 in the first half of 2020. In January, we hired a chief commercial officer to build out our market access and commercial team for the anticipated launch of B-VEC and also broke ground on our second cGMP manufacturing facility, ASTRA, a 100,000 square foot facility that will be built-out and validated over the next 12-15 months to serve our future pipeline products. On the research front, our research, clinical and regulatory teams are working to initiate a Phase 1 clinical study in an aesthetic skin indication and file an IND for a third rare disease indication in the second half of 2020. “2019 was a busy year for Krystal as we worked to become fully-integrated in the gene therapy space. On the clinical front, we announced positive results from the Phase 1/2 results of B-VEC to treat DEB and the initiation of a Phase 1/2 clinical study of KB105 for the treatment of TGM1-deficient autosomal recessive congenital ichthyosis (“ARCI”) in October. On the manufacturing front, we initiated manufacturing of our Phase 3 clinical material at ANCORIS, our first cGMP facility for the clinical and future commercial production of B-VEC, that was completed early in 2020. We strengthened our patent portfolio with the issuance of our first foreign patent for B-VEC and broadened our platform patent for skin-targeted therapeutics as well as methods of its use for delivering any effector of intere...