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Kodiak Sciences to Present KSI-101 Highlights at 2025 Congress of the International Ocular Inflammation Society
PALO ALTO, Calif., June 25, 2025 /PRNewswire/ -- Kodiak Sciences Inc. (Nasdaq: KOD), a biopharmaceutical company committed to researching, developing and
About this update from Kodiak Sciences Inc
[{"type":"text","content":"PALO ALTO, Calif., June 25, 2025 /PRNewswire/ -- Kodiak Sciences Inc. (Nasdaq: KOD), a biopharmaceutical company committed to researching, developing and commercializing transformative therapeutics to treat a broad spectrum of retinal diseases, announced today that management along with key opinion leaders will present KSI-101 highlights at the 2025 Congress of the International Ocular Inflammation Society (IOIS) in Rio de Janeiro, Brazil on Friday, June 27, 2025.\n\n\"We are excited to participate in this year's IOIS meeting and connect with leading experts in ocular inflammation to help advance care for patients with macular edema caused by inflammation,\" said Pablo Velazquez-Martin, MD, Chief Medical Officer of Kodiak Sciences.\nMacular Edema Secondary to Inflammation (MESI) represents a set of serious ocular inflammatory conditions that can cause significant vision loss. Macular edema occurs when inflammation disrupts the blood-retinal barrier, increasing vascular permeability and causing fluid to accumulate in the retina, resulting in macular edema. The inflammation can be triggered by various underlying causes including autoimmune diseases, uveitis or post-surgical inflammation following procedures like cataract surgery. In many cases, the underlying cause of inflammation is not identified. Steroids are commonly used to manage MESI, but they carry the risk of serious, long-lasting ocular side effects, particularly with long-term or high-dose use.\n\"Inflammation and macular fluid indicate that both interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) play a synergistic role in driving macular edema and inflammation, but there are no intravitreal biologic therapies that target both underlying disease mechanisms. Managing macular edema secondary to inflammation today is challenging and represents an area of significant need for improvement in today's treatment approach,\" continued Dr. Velazquez-Martin.\n\"Together with key opinion leaders, we will share insights into the pathophysiology of macular edema secondary to inflammation, discuss the limitations of current treatment options, highlight real-world case examples of patients and present promising clinical data on KSI-101, a first-in-class, high-strength, bispecific investigational intravitreal biologic designed to target both IL-6 and VEGF simultaneously ...