Business
KalVista Pharmaceuticals Provides Operational and Financial Update
– Response to Coronavirus Impact on Ongoing Clinical Trials – – Cash Runway Extended into 2022 – CAMBRIDGE, Mass. & SALISBURY, England--(BUSINESS WIRE)--
About this update from Kalvista Pharmaceuticals, Inc.
[{"type":"text","content":"\n– Response to Coronavirus Impact on Ongoing Clinical Trials –\n\n\n– Cash Runway Extended into 2022 –\n\n CAMBRIDGE, Mass. & SALISBURY, England--(BUSINESS WIRE)--\nKalVista Pharmaceuticals, Inc. (NASDAQ:KALV), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of small molecule protease inhibitors, today announced potential impact of coronavirus disease 2019 (COVID-19) on its ongoing operations and provided revised financial guidance that activities are funded into at least early 2022.\n\n\n“Patient safety remains our top priority,” said Andrew Crockett, Chief Executive Officer of KalVista. “The Phase 2 clinical trial for KVD900 as an on-demand oral therapy for HAE attacks remains active, but we anticipate a delay in timing of data due to the unprecedented worldwide impact of COVID-19. A number of our participating physicians and clinical sites have shifted their focus to address the pandemic, and patients also are dealing with challenges that may limit their ability to participate. We offer all of these groups our full support and appreciation during this time, and we are working closely with all of them to follow changing regulatory, institutional and governmental policies to navigate through this situation. Assuming that participants are able to resume their activity during the second quarter of 2020, we anticipate we will provide results in the second half of 2020. To enhance our financial strength until we have further clarity, we have revised our projected spend and now expect our funding to last into at least early 2022.”\n\n\nKVD900 is being developed as an on-demand oral therapy for the treatment of HAE attacks. The ongoing Phase 2 trial is being conducted in approximately 20 sites in Europe and the U.S. and is a placebo-controlled, crossover study designed to evaluate the safety and efficacy of KVD900. Patients in the study treat a total of two eligible attacks, taking the medication at home after a telephone consultation with the investigator to confirm eligibility of the attack. Patients do not need to treat sequential attacks, and the intermittent dosing regimen allows those whose participation is paused by the ongoing crisis to remain active in the study and resume dosing as it becomes appropriate. The data collected to date is not affected by any potential delays...