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Significant Positive Results with Jaguar Health's Crofelemer for Chronic Refractory Diarrhea in IBS-D, Presented at American College of Gastroenterology Annual Meeting
It is estimated that 10-15% of people in the United States have IBS SAN FRANCISCO, CA / ACCESSWIRE / October 29, 2024 / Jaguar Health, Inc.(NASDAQ:JAGX)
About this update from Jaguar Health, Inc.
[{"type":"text","content":"It is estimated that 10-15% of people in the United States have IBS SAN FRANCISCO, CA / ACCESSWIRE / October 29, 2024 / Jaguar Health, Inc.(NASDAQ:JAGX) (\"Jaguar\") family company Napo Pharmaceuticals (\"Napo\") today announced that the abstracts are now available for two independent investigator-initiated studies of crofelemer, Napo's novel, plant-based oral prescription drug, that show a benefit in patients with chronic refractory diarrhea and are the subject of poster presentations taking place today, October 29, 2024, at the American College of Gastroenterology Annual Scientific Meeting (ACG 2024) in Philadelphia, Pennsylvania. Descriptions of both studies appear below, along with a link to the virtual ACG 2024 ePoster Hall page for each study - which display the poster for each study and provide a short audio presentation of the posters.\"We are very excited that crofelemer continues to demonstrate clinical robustness in responder analysis trials for multiple gastroenterological conditions - including functional diarrhea and chronic idiopathic diarrhea. We are inspired to address the unmet needs, unmet symptom management, and patient comfort in these populations, which are often considered subgroups of diarrhea-predominant irritable bowel syndrome (IBS-D),\" commented Lisa Conte, President and CEO of Jaguar.Crofelemer has been the subject of two previously presented Phase 2 trials in IBS-D. Additionally, as announced, the recently completed analysis of the prespecified subgroup of adult patients with breast cancer from our Phase 3 OnTarget trial of crofelemer for cancer therapy-related diarrhea indicate that crofelemer achieved statistical significance in this subgroup. The breast cancer results from OnTarget are also a responder analysis, and this data has been submitted by the study's primary investigators to a relevant oncology conference for consideration for a presentation.Study: Pilot Study of Crofelemer for Functional DiarrheaLink to Study Poster & Audio Presentation: Click HereCrofelemer significantly decreased stool consistency and abdominal pain without significant side effects, including constipation, in this small crossover study of 17 patients with functional diarrhea. The study showed that crofelemer may be a particularly useful option in those patients without a significant pain component to their symptoms, ...