Jaguar Health’s Subsidiary Napo EU Changes Name to Napo Therapeutics, Reflecting the Italian Company’s Focus on Rare Diseases & Orphan Drugs

About this update from Jaguar Health, Inc.

[{"type":"text","content":"SAN FRANCISCO, CA / ACCESSWIRE / December 20, 2021 / Jaguar Health, Inc. (NASDAQ:JAGX) today announced that the name of its majority owned subsidiary changed from Napo EU S.p.A. to Napo Therapeutics S.p.A. effective December 17, 2021. Napo Therapeutics is a European specialty drug development and marketing company based in Milan, Italy.\"Our mission at Napo Therapeutics is to provide access to Jaguar Health's proprietary first-in-class plant-based medicine crofelemer in Europe to address significant rare disease indications - and our initial focus is on clinical development and future registration in Europe of crofelemer for two debilitating orphan target indications: Short bowel syndrome with intestinal failure (SBS-IF) and congenital diarrheal disorders (CDD). We believe Napo Therapeutics will support and facilitate expanded and accelerated patient access to a novel therapy. The name-change to Napo Therapeutics reflects our focus on rare diseases and orphan-drugs,\" commented Massimo Mineo, General Manager of Napo Therapeutics.Crofelemer is a novel, plant-based oral chloride ion channel modulator that boasts a unique anti-secretory mechanism of action, acting locally in the gastrointestinal tract to modulate and normalize the patient's waterflow.\"Normal functioning of the small intestine is crucial to optimize a patient's absorption of fluids and nutrients to support life. Crofelemer's ability to regulate ion channels in the gut normalizes the salt and water balance in the small intestine, which may lead to better absorption of fluids and nutrients in those living with SBS-IF,\" Mr. Mineo said.Napo Therapeutics is pursuing the accelerated conditional marketing authorization pathway from the European Medicines Agency (EMA) for crofelemer for short bowel syndrome (SBS) under orphan-drug designation (ODD).As announced December 13, 2021, the EMA has granted ODD for crofelemer for the SBS indication in the European Union following review of the ODD application Napo Therapeutics submitted to the EMA this past September. Following this decision from the EMA, Napo Therapeutics is initiating efforts to plan and commence a pivotal clinical trial of crofelemer in both adult and pediatric SBS patients in support of the company's key focus on pursuing the EMA's accelerated conditional marketing authorization pathway in Europe for this rar...

More updates from Jaguar Health, Inc.