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Jaguar Health Provides Updates on Canalevia (Crofelemer), the First Plant-based Prescription Medicine Under Development for Chemotherapy-induced Diarrhea in Dogs and Exercise-induced Diarrhea in Dogs
Canalevia would be first and only FDA-approved plant-based medicine for dogs that suffer from diarrhea during chemotherapyCanalevia will be available by
About this update from Jaguar Health, Inc.
[{"type":"text","content":"Canalevia would be first and only FDA-approved plant-based medicine for dogs that suffer from diarrhea during chemotherapyCanalevia will be available by fourth quarter 2021, if conditionally approvedSAN FRANCISCO, CA / ACCESSWIRE / May 18, 2021 / Jaguar Health, Inc. (NASDAQ:JAGX) (\"Jaguar\" or the \"Company\") today provided updates regarding the development program for the Company's oral plant-based drug candidate Canalevia™ (crofelemer delayed-release tablets) to treat chemotherapy-induced diarrhea (CID) in dogs and exercise-induced diarrhea (EID) in dogs. There currently is no FDA-approved anti-secretory prescription product to manage these types of debilitating diarrhea in dogs.\"We are pleased to report our progress on Canalevia, which has the potential to help thousands of dogs experiencing diarrhea due to chemotherapy,\" said Michael Guy, DVM, Ph.D., Jaguar's vice president of preclinical and nonclinical studies. \"With feedback from the FDA's Center for Veterinary Medicine (CVM), we've completed the submission of updated versions of required minor and major technical sections of Jaguar's application for conditional approval of Canalevia for CID under The Minor Use and Minor Species (MUMS) Animal Health Act of 2004. We are planning for the expected regulatory approval and commercialization of Canalevia under conditional approval for CID in the fourth quarter of 2021.\"\"Management of this type of debilitating diarrhea in dogs undergoing cancer treatment is a comfort issue for dogs. Additionally, diarrhea management may also help dogs better tolerate their chemotherapy and improve the home and living environment for dog owners,\" said Lisa Conte, Jaguar's president and chief executive officer and parent of two Jack Russell Terriers. \"We are excited to report our progress on this first-of-its-kind medicine and believe Canalevia will be an important treatment option for veterinary healthcare teams and dog owners once approved.\"The Company is also in the process of completing the submission package for EID for regulatory approval and commercialization in the same time frame. Working dogs, including search and rescue, military, and sled dogs, often suffer diarrhea as a result of engaging in long periods of intense, off-leash exercise.\"Elite athletes of all species tend to have more diarrhea than their healthy but more sede...