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Issuance of New European & Australian Patents Bolster IP Protection for Jaguar Health in the Treatment of Short Bowel Syndrome (SBS) and Congenital Diarrheal Disorders (CDDs)
New patents issued for core rare disease target indications for crofelemerNapo has approximately 200 patents issued and pendingJaguar is supporting
About this update from Jaguar Health, Inc.
[{"type":"text","content":"New patents issued for core rare disease target indications for crofelemerNapo has approximately 200 patents issued and pendingJaguar is supporting investigator-initiated proof-of-concept studies of crofelemer for the rare disease indications of SBS and microvillus inclusion disease (MVID), an ultrarare CDD, in the US, EU, and Middle East/North Africa regions, with results expected in 2024 and 2025 SAN FRANCISCO, CA / ACCESSWIRE / July 8, 2024 / Napo Pharmaceuticals (Napo), a Jaguar Health (NASDAQ:JAGX) (Jaguar) family company, today announced that the European Patent Office and IP Australia, the Australian patent office, have each issued a new patent to Napo. The European patent covers methods for treating SBS, bile acid diarrhea, and diarrhea associated with small intestine resection or gallbladder removal, in patients with an inhibitor of chloride-ion transport such as crofelemer, Napo's novel plant-based prescription drug. The Australian patent covers methods of preventing, ameliorating and/or treating diarrhea associated with CDDs using a proanthocyanidin polymer composition such as crofelemer.\"We are very happy that these patents have been issued and believe that they further enhance our intellectual property protection for crofelemer for our core rare disease target indications of SBS and MVID,\" said Lisa Conte, Jaguar's founder, president, and CEO.\"As previously announced, Jaguar, with strong leadership and participation from Jaguar family companies Napo and Napo Therapeutics, is supporting investigator-initiated proof-of-concept studies of crofelemer for SBS with intestinal failure and MVID in the US, EU and Middle East/North Africa (MENA) regions, with results expected in 2024 and 2025,\" Conte said. \"In accordance with the guidelines of specific EU countries, published data from clinical investigations in SBS and MVID could support early patient access to crofelemer for these debilitating conditions in those countries.\"Some SBS patients are subject to intestinal failure, often requiring parenteral nutrition (PN) from a few days up to 7 days a week. Intestinal failure is associated with significant morbidity and mortality; and high medical expenses associated with PN. SBS patients with intestinal failure also have severe chronic diarrhea, and the associated sequelae from diarrhea, including significant dehydration...