Business
Intellia Therapeutics Announces Second Quarter 2023 Financial Results and Highlights Recent Company Progress
Completed identification of all patients for the Phase 2 study of NTLA-2002 for the treatment of hereditary angioedema (HAE) Plans to initiate a global
About this update from Intellia Therapeutics, Inc.
[{"type":"text","content":"Completed identification of all patients for the Phase 2 study of NTLA-2002 for the treatment of hereditary angioedema (HAE) Plans to initiate a global pivotal Phase 3 study of NTLA-2002 as early as Q3 2024, subject to regulatory feedback On track to submit IND application in September for a global pivotal study of NTLA-2001 for the treatment of transthyretin (ATTR) amyloidosis with cardiomyopathy; study initiation anticipated by year-end 2023, subject to regulatory feedbackPlans to present additional clinical data in 2023 from the ongoing NTLA-2001 first-in-human study by year-end Expects to submit a Clinical Trial Application (CTA) by year-end for NTLA-3001, Intellia’s first in vivo insertion candidate, in development for the treatment of alpha-1 antitrypsin deficiency (AATD)-associated lung diseaseEnded the second quarter of 2023 in a strong financial position with approximately $1.1 billion in cash CAMBRIDGE, Mass., Aug. 03, 2023 (GLOBE NEWSWIRE) -- Intellia Therapeutics, Inc. (NASDAQ:NTLA), a leading clinical-stage genome editing company focused on developing potentially curative therapies leveraging CRISPR-based technologies, today reported operational highlights and financial results for the second quarter ended June 30, 2023. “We continue to make significant and rapid progress in the development of our first two in vivo, CRISPR-based therapeutic candidates,” said Intellia President and Chief Executive Officer John Leonard, M.D. “For NTLA-2002, we are thrilled to see the excitement for this investigational therapy from the HAE community. In just a handful of months, we were able to identify all patients required to fully enroll the ongoing Phase 2 study and now expect to initiate the pivotal Phase 3 program next year. For NTLA-2001, our team has been working diligently to prepare for an IND submission in September and to begin the Phase 3 study for the cardiomyopathy manifestation of ATTR amyloidosis before the end of this year. Overall, we continue to believe that NTLA-2001 and NTLA-2002 represent only the beginning for our pipeline and platform as additional in vivo and ex vivo candidates advance toward the clinic.” Second Quarter 2023 and Recent Operational Highlights In Vivo Program Updates Transthyretin (ATTR) Amyloidosis NTLA-2001: NTLA-2001 is an in vivo, systemically delivered, investigational CRISPR-based therapy...