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Innovation Pharmaceuticals Partnering Provides Momentum For Inflammatory Bowel Disease Programs, Targeting a Substantial and Prized Market with a Large Unmet Patient Need
Innovation Pharmaceuticals Partnering Provides Momentum For Inflammatory Bowel Disease Programs, Targeting a Substantial and Prized Market with a Large Unmet Patient Need.
About this update from Innovation Pharmaceuticals Inc.
[{"type":"text","content":"\n Convened first Joint Development Committee (JDC) meetingData generated to inform internal Brilacidin development efforts in Ulcerative ColitisGoal to develop oral Brilacidin to treat a wide continuum of GI diseases in GI market estimated to hit $48.4 Billion by 2022Brilacidin tablet for UC clearly differentiated as oral, non-biologic, non-corticosteroid, targeted UC drug candidate BEVERLY, Mass., Oct. 14, 2019 (GLOBE NEWSWIRE) -- Innovation Pharmaceuticals (OTCQB:IPIX) (“the Company”), a clinical stage biopharmaceutical company, is pleased to announce positive momentum in its efforts to advance programs utilizing Brilacidin for Inflammatory Bowel Disease (IBD).  The Company’s goal is to develop Brilacidin as a novel, non-corticosteroid, non-biologic orally-delivered drug capable of treating a wide continuum of GI diseases, to the benefit of patients and shareholders alike. The first Joint Development Committee (JDC) meeting with Alfasigma S.p.A.—an Italy-based global pharmaceutical company that licensed worldwide rights to develop Brilacidin for localized treatment in Ulcerative Proctitis/Ulcerative Proctosigmoiditis (UP/UPS)—was recently convened. The JDC is responsible for reviewing, discussing and approving activities related to advancing Brilacidin in UP/UPS. There is a great need for novel treatments capable of achieving remission in distal colitis via enema, as evidenced by Food and Drug Administration (FDA) registration trials for Salix Pharmaceutical’s UCERIS®, a corticosteroid that showed 2mg rectal foam (foam enema) achieved modest remission rates of distal colitis at six weeks. Salix was acquired by Valeant Pharmaceuticals in 2015 for $14.5 billion. Alfasigma, with proven expertise in treating IBD and substantial commercial capabilities, is well-positioned to advance Brilacidin toward regulatory approval in UP/UPS, a $1.4 billion market with the current standard-of-care comprising 5-aminosalicyclic acid (5-ASA) and steroid treatments. If successful, milestone-based payments totaling $24 million, plus royalties, would be paid to Innovation. Through strategic partnering with BDD Pharma, preparations continue for initiation in December of a planned Phase 1 clinical trial of oral Brilacidin in the Ulcerative Colitis (UC) program. Data generated under this partnership in UP/...