Health
Indivior Presents New Data at CPDD Demonstrating that High Buprenorphine Exposure May Improve Treatment Outcomes in High Fentanyl Users
Indivior PLC (Nasdaq: INDV) presented new findings this week at the College on Problems of Drug Dependence (CPDD) Annual Scientific Meeting. A post hoc analysis showed that patients with heavier fentanyl use experienced clinically meaningful improvements in opioid abstinence when treated with a 300 mg maintenance dose of SUBLOCADE, compared to the 100 mg dose. While the 300 mg dose did not demonstrate a statistically significant advantage over 100 mg for weekly abstinence—the study's primary end
About this update from Indivior Pharmaceuticals, Inc.
[{"type":"list","items":[{"val":[{"type":"text","content":"A post-hoc analysis demonstrates that buprenorphine exposure with 300 mg SUBLOCADE® (buprenorphine extended-release) may improve treatment outcomes among opioid use disorder (OUD) patients with heavy fentanyl use1","length":213,"tagName":"p"}]},{"val":[{"type":"text","content":"Additional Indivior-funded research identified OUD treatment barriers in American Indian/Alaska Native (AI/AN) people who are often affected by higher drug overdose death rates compared to other racial and ethnic groups2-5","length":222,"tagName":"p"}]}],"tagName":"ul","bulletedList":true,"length":435,"olType":false},{"type":"text","content":"RICHMOND, Va., June 19, 2025 /PRNewswire/ -- Indivior PLC (Nasdaq: INDV) presented new findings this week at the College on Problems of Drug Dependence (CPDD) Annual Scientific Meeting. A post hoc analysis showed that patients with heavier fentanyl use experienced clinically meaningful improvements in opioid abstinence when treated with a 300 mg maintenance dose of SUBLOCADE, compared to the 100 mg dose. While the 300 mg dose did not demonstrate a statistically significant advantage over 100 mg for weekly abstinence—the study's primary endpoint—in the overall population with moderate to severe opioid use disorder (OUD), the results suggest that higher doses of SUBLOCADE may offer better outcomes for individuals with high levels of fentanyl use.","length":768,"tagName":"p"},{"type":"image","alt":"Indivior (PRNewsfoto/Indivior)","displaySize":"","headline":null,"caption":"Indivior (PRNewsfoto/Indivior)","className":"","disableSlideshowImg":false,"size":{"original":{"width":400,"height":130,"url":"https://media.zenfs.com/en/prnewswire.com/e9a6eb17aaf44dddfab6f7d13d2315b7"},"resized":{"url":"https://s.yimg.com/ny/api/res/1.2/.uJSnzZQQuSzYp3kZpAAsQ--/YXBwaWQ9aGlnaGxhbmRlcjt3PTcwNTtoPTIyOTtjZj13ZWJw/https://media.zenfs.com/en/prnewswire.com/e9a6eb17aaf44dddfab6f7d13d2315b7","width":400,"height":130}},"href":"https://mma.prnewswire.com/media/1814851/Indivior_Logo.html","hrefExternal":true,"rel":"nofollow"},{"type":"text","content":""These findings offer additional evidence that the higher maintenance dose of SUBLOCADE is safe and may better support patients with intense fentanyl use patterns," said Christian Heidbreder, Ph.D., Chief Scientific Officer at Indivior. &quo...