Business
Efforts in fight vs Covid-19 with Lupuzor; Ureka
Efforts in fight vs Covid-19 with Lupuzor; Ureka.
About this update from Immupharma Plc
[{"type":"text","content":"\n \n \n RNS Number : 8372M\n Immupharma PLC\n 14 May 2020\n \n \n \n \n \n \n \n \n \n \n RNS: FOR IMMEDIATE RELEASE 14 May 2020\n \n \n \n \n \n \n \n \n ImmuPharma PLC\n \n \n (\"ImmuPharma\" or the \"Company\")\n \n \n \n \n \n ImmuPharma's efforts in the fight against Covid-19 with Lupuzor™ and Ureka\n \n \n \n \n \n ImmuPharma PLC (LSE:IMM), (Euronext Growth Brussels: ALIMM), the specialist drug discovery and development company provides a progress update on activities around Covid-19.\n \n \n \n \n \n On 30 March 2020, ImmuPharma announced that it had expanded its pipeline to include three new 'Anti-Infective' programs, one of which was in 'Antivirals'. Investigation of the application of the Ureka peptide technologies within this Antivirals program suggests the potential to create effective anti-fusion peptides with the goal to prevent virus entry into the host cells, which may lead to novel peptide based antiviral therapies. Further exploratory work continues on this program.\n \n \n \n \n \n As part of an overall evaluation of how we might apply our patented technologies to the fight against the Covid-19 epidemic, within our 'Autoimmunity' therapy area, we have also been considering the unique way that Lupuzor\n ™ interacts with the immune system and any potential application to Covid-19.\n \n \n \n \n \n In this respect we note the results* of a recent study conducted at Emory University Atlanta GA, suggesting that Covid-19 (SARS-COV-2) patients and systemic lupus erythematosus (SLE) patients experiencing flares might share similar inflammatory symptoms, underpinned by similar mechanisms (role of cytokines). Lupuzor\n ™\n is a modulator of the immune response and an anti-inflammatory agent, which has activity against SLE (lupus), an autoimmune disease, as well as against other inflammatory diseases. \n ImmuPharma, together with \n its US licencing partner, Avion Pharmaceuticals, will be progressing Lupuzor\n ™ into\n a new optimised international Phase III trial this year in lupus patients. \n \n \n \n \n \n *\"Critically ill SARS-CoV-2 patients display lupus-like hallmarks of extraordinary B cell activation\" -\n \n https://doi.org/10.1101/2020.04.29.20083717\n \n .\n \n \n \n \n \n Given the findings of the Atlanta r...