Business
Immuneering Reports First Quarter 2022 Financial Results and Recent Business Highlights
IND filing for IMM-1-104 expected in Q3 2022; Enrollment of the first patient expected in Q4 2022 IND filing for IMM-6-415, designed to sensitize resistant
About this update from Immuneering Corporation
[{"type":"text","content":"IND filing for IMM-1-104 expected in Q3 2022; Enrollment of the first patient expected in Q4 2022 IND filing for IMM-6-415, designed to sensitize resistant tumors to select immunotherapies, expected in 2023 Cash, cash equivalents and marketable securities of $137.8M is expected to provide cash runway into Q3 2024 CAMBRIDGE, Mass., May 10, 2022 (GLOBE NEWSWIRE) -- Immuneering Corporation (NASDAQ: IMRX), a biopharmaceutical company using translational bioinformatics to advance a pipeline of product candidates designed to benefit large populations of patients with cancer and other diseases, today reported financial results for the first quarter ended March 31, 2022 and provided recent business highlights. “We believe IMM-1-104 has great potential to benefit the many cancer patients with tumors driven by RAS mutations. We are thrilled to be gearing up to file our IND for IMM-1-104, which remains on track to be filed in the third quarter of 2022, and we expect to enroll our first patient in the Phase 1 trial in the fourth quarter of 2022. To date, we have generated compelling preclinical results across a broad range of animal tumor models including KRAS-G12C, KRAS-G12D, KRAS-G12S, NRAS-Q61R, and BRAF-V600E mutations. In totality, this compelling preclinical data package demonstrates IMM-1-104’s potential to have broad activity that is independent of the specific mutation activating the MAPK pathway.” said Ben Zeskind, Ph.D., MBA, chief executive officer of Immuneering Corporation. Corporate Highlights IMM-1-104 Observed Greater Tumor Growth Inhibition Compared to Binimetinib in a NRAS Mutant Melanoma Model: In January 2022, Immuneering presented preclinical data in a presentation titled “Head-to-Head Comparison of the Dual-MEK Inhibitor IMM-1-104 Versus Binimetinib in NRAS Mutant Melanoma Models,” by Peter King, PhD, Vice President and Head of Discovery. In the SK-MEL-2 melanoma xenograft mouse model exhibiting the NRAS-Q61R mutation, IMM-1-104 demonstrated superior tumor growth inhibition relative to binimetinib (binimetinib was tested versus dacarbazine in the Phase 3 NEMO trial). Immuneering also hosted a key expert event with Dr. Anna Pavlick, a leading melanoma expert, to discuss the NRAS mutant melanoma treatment landscape. A replay of the key expert event can be accessed at: https://ir.immuneering.com/news-events/events-presen...