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Nexcella, an Immix Biopharma Subsidiary, Announces New Positive NXC-201 Clinical Data Demonstrating 100% Complete Responses in AL Amyloidosis Patients + Additional Positive Multiple Myeloma Safety Data Demonstrating NXC-201 Outpatient CAR-T Treatment ...
Nexcella, an Immix Biopharma Subsidiary, Announces New Positive NXC-201 Clinical Data Demonstrating 100% Complete Responses in AL Amyloidosis Patients +
About this update from Immix Biopharma, Inc.
[{"type":"text","content":"Nexcella, an Immix Biopharma Subsidiary, Announces New Positive NXC-201 Clinical Data Demonstrating 100% Complete Responses in AL Amyloidosis Patients + Additional Positive Multiple Myeloma Safety Data Demonstrating NXC-201 Outpatient CAR-T Treatment Potential \n LOS ANGELES, March 23, 2023 (GLOBE NEWSWIRE) -- Nexcella, Inc., a subsidiary of Immix Biopharma, Inc. (Nasdaq: IMMX) (“ImmixBio”, “Company”, “We” or “Us”) today announced that NXC-201 treatment continues to demonstrate 100% complete hematologic responses and 100% organ response rate – cardiac, renal, liver response – in a total of 8 AL amyloidosis patients (an additional 2 patients maintaining 100% complete response). Additionally, Nexcella announced new positive safety data in relapsed/refractory multiple myeloma demonstrating outpatient CAR-T treatment potential. To date, 58 patients have been treated with NXC-201, 50 in multiple myeloma, and 8 in AL amyloidosis. The $13.9 billion Multiple Myeloma market in 2017 is expected to reach $28.7 billion in 2027 according to Wilcock, et al. Nature Reviews. The Amyloidosis market was $3.6 billion in 2017, expected to reach $6 billion in 2025, according to Grand View Research. “We’re extremely excited with the results we’re seeing. We are making significant advancements with NXC-201 against the backdrop of the current standard of care in these large markets,” said Gabriel Morris, President, Nexcella, Inc. \"In Multiple Myeloma, our 90% overall response rate continues to attract the attention of key opinion leaders globally. We have accumulated clinical data from 50 patients and counting,” said Ilya Rachman, MD, PhD, Executive Chairman, Nexcella, Inc. “In AL Amyloidosis, our 100% complete response rate with 100% organ responses across cardiac, renal and liver organ systems fuels our continued excitement. NXC-201’s positive safety profile to-date could enable outpatient treatment in the thousands of U.S. community hospitals who today are unable to dose CAR-Ts.” About NXC-201 NXC-201 (formerly HBI0101) is a BCMA-targeted investigational chimeric antigen receptor T (CAR-T) cell therapy that is being studied in a comprehensive clinical development program for the treatment of patients with relapsed or refractory multiple myeloma and AL amyloidosis. The design consists of a structurally differentiated CAR-T with our proprietary BCMA-...