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Humacyte Announces JAMA Surgery Publication Highlighting Potential of Human Acellular Vessel™ (HAV™) to Expand Vascular Trauma Reconstruction and Bypass Treatment Options
-- HAV implanted in nearly 500 patients with more than 1,000 patient-years of follow up to date, for treatment of peripheral arterial disease, arteriovenous
About this update from Humacyte, Inc.
[{"type":"text","content":"-- HAV implanted in nearly 500 patients with more than 1,000 patient-years of follow up to date, for treatment of peripheral arterial disease, arteriovenous access for hemodialysis, and trauma – -- Immediately-available HAV, if approved, would represent significant and innovative advancements for vascular repair and replacement conduits-- DURHAM, N.C., June 29, 2022 (GLOBE NEWSWIRE) -- Humacyte, Inc. (Nasdaq: HUMA), a clinical-stage biotechnology platform company developing universally implantable bioengineered human tissue at commercial scale, today announced that an analysis of the potential of the Human Acellular Vessel (HAV) to expand vascular surgical treatment options has been published online in the Journal of the American Medical Association (JAMA) companion journal Surgery. Humacyte’s HAVs are engineered replacement vessels designed to be durable, infection-resistant and off-the-shelf to address long-standing limitations in vessel tissue repair and replacement. The HAV is currently being evaluated in late-stage clinical trials in vascular trauma repair, arteriovenous access for hemodialysis, and peripheral arterial disease (PAD). To date, the HAV has been implanted in nearly 500 patients, with more than 1,000 patient-years of follow up across seven clinical trials, including 31 cases performed under an authorized U.S. Food and Drug Administration’s (FDA) Expanded Access Program (EAP). The JAMA Surgery manuscript, entitled “The Human Acellular Vessel (HAV) for Vascular Reconstruction and Bypass,” reviews the clinical need for improved options for vascular reconstruction and bypass conduits, and the potential advantages of the HAV over existing approaches. “The current standard of care for vascular reconstruction or bypass procedures requiring a replacement vessel often involves autologous vein harvesting, which is associated with wound complications, or using a synthetic vascular conduit, which has demonstrated unfavorable compliance to native vessels,” said Todd E. Rasmussen, M.D., FACS, (Col, ret. USAF MC), manuscript co-author, and Professor and Vice-Chair for education in the department of surgery and a senior associate consultant in the division of vascular and endovascular surgery at Mayo Clinic. “While there have been tremendous advancements in vascular surgery in the past few decades, the HAV represents the first...