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Humacyte Announces Allowance of U.S. Patent Covering BioVascular Pancreas (BVP™)
- New U.S. patent covers the design and composition of the BVP - - Positive results from ongoing preclinical studies support the potential of the BVP to
About this update from Humacyte, Inc.
[{"type":"text","content":"- New U.S. patent covers the design and composition of the BVP - - Positive results from ongoing preclinical studies support the potential of the BVP to deliver insulin-producing islets as a potential treatment for type 1 diabetes - DURHAM, N.C., Sept. 19, 2024 (GLOBE NEWSWIRE) -- Humacyte, Inc. (Nasdaq: HUMA), a clinical-stage biotechnology platform company developing universally implantable, bioengineered human tissue at commercial scale, today announced the allowance of a U.S. Patent covering its BioVascular Pancreas (BVP) product candidate for the treatment of type 1 diabetes. The BVP is designed to enable the delivery and survival of insulin-producing islets inside the body, using Humacyte’s investigational acellular tissue engineered vessel (ATEV™) as a carrier for the islets. The new U.S. Patent, titled “Bioartificial Vascular Pancreas,” covers the design and composition of the BVP. The patent is owned by Yale University and is exclusively licensed to Humacyte. Approximately 1.45 million Americans are currently living with type 1 diabetes, with 64,000 more Americans diagnosed each year. The incidence of type 1 diabetes is on the rise worldwide, impacting the lives of millions and causing significant economic burden. The disease requires constant vigilance and measurement of blood sugars, with patients having to continuously balance insulin intake throughout the day. While insulin management can regulate blood glucose levels and keep people alive, continuous and lifelong monitoring of blood sugar is difficult for patients who have no islets of their own to automatically control blood sugar levels. The BVP is designed to enable the delivery and survival of insulin-producing islets inside the body. Such technology could overcome many of the hurdles currently associated with implantation of islets into diabetic patients. In June 2024, Humacyte reported positive results from two sets of ongoing preclinical studies, supporting the potential of the BVP product candidate to deliver insulin-producing islets as a treatment for type 1 diabetes. At a presentation at the Breakthrough T1D Beta Cell Consortium Meeting, Humacyte’s scientists presented data in which stem cell-derived islets restored normal blood sugar in diabetic mice. Islets manufactured from human stem cells may provide the basis for the islets that are ultimately deliv...