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Hoth Therapeutics Initiates Preclinical Study Including Topical Form of Aprepitant for Dermatological Treatment Relating to Side Effects of Cancer Medication

NEW YORK, Nov. 14, 2019 /PRNewswire/ -- Hoth Therapeutics, Inc. (Nasdaq: HOTH) ("HOTH" or the "Company"), a biopharmaceutical company focused on developing

articleHoth Therapeutics, Inc.November 14, 20195/company/hoth-therapeutics-inc/news/hoth-therapeutics-initiates-preclinical-study-including-topical-form-of-aprepitant-for-dermatological-treatment-relating-to-side-effects-of-cancer-medication
Hoth Therapeutics Initiates Preclinical Study Including Topical Form of Aprepitant for Dermatological Treatment Relating to Side Effects of Cancer Medication

About this update from Hoth Therapeutics, Inc.

[{"type":"text","content":"NEW YORK, Nov. 14, 2019 /PRNewswire/ -- Hoth Therapeutics, Inc. (Nasdaq: HOTH) (\"HOTH\" or the \"Company\"), a biopharmaceutical company focused on developing new generation therapies for dermatological disorders such as atopic dermatitis, chronic wounds, psoriasis and acne, today announced, in partnership with the George Washington University (GW), the initiation of a preclinical study of Aprepitant for dermatological treatment relating to the side effects of cancer medication.\n\n \nIn July 2019, HOTH and GW announced its working relationship and entering into an exclusive license option agreement pertaining to its intellectual property on the use of Aprepitant in treating skin-related and other side effects from drugs used to treat cancer. Traditionally, Aprepitant is utilized along with other medications to help prevent nausea and vomiting caused by cancer drug treatment chemotherapy by blocking the cause and one of the body's natural substances, neurokinin-1.\nMr. Robb Knie, CEO of Hoth Therapeutics, commented, \"Initial findings by our team and GW on the positive dermatological effects of Aprepitant in cancer patients have been fascinating. We are pleased today to launch this study to continue our exploration of this possible treatment. Hoth looks forward to our initial data read-out and further testing with our partners at the George Washington University.\"\nUnder the terms of the agreement, HOTH has the option to exclusively license two U.S. patents covering methods of using Aprepitant and other drugs that inhibit this neurokinin-1 function. Based on early data findings from HOTH and GW, this preclinical study is being initiated to continue exploring the dermatological benefits of Aprepitant in cancer patients who receive chemotherapy.\nAbout Hoth Therapeutics, Inc.Hoth Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing new generation therapies for dermatological disorders. HOTH's pipeline has the potential to improve the quality of life for patients suffering from indications including atopic dermatitis, chronic wounds, psoriasis, and acne. HOTH has the exclusive worldwide rights to BioLexa, the company's proprietary lead drug candidate topical platform that uniquely combines two FDA approved compounds to fight bacterial infections across multiple indications. HOTH is preparing to l...

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