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Summit Therapeutics Announces Clinical Trial Collaboration with GSK to Evaluate Ivonescimab in Combination with GSK’s B7-H3 Antibody Drug Conjugate (ADC)

MIAMI, January 12, 2026--Summit Therapeutics Inc. (NASDAQ: SMMT) today announced it has entered into a clinical trial collaboration with GSK plc ("GSK", LSE/NYSE: GSK) to evaluate ivonescimab, a novel, investigational PD-1 / VEGF bispecific antibody, in combination with risvutatug rezetecan (also known as GSK’227), GSK’s novel investigational B7-H3 targeting antibody drug conjugate (ADC), across multiple solid tumor settings, including small cell lung cancer (SCLC).

articleGsk PlcJanuary 12, 20269/company/glaxosmithkline-plc/news/summit-therapeutics-announces-clinical-trial-collaboration-with-gsk-to-evaluate-ivonescimab-in-combination-with-gsks-b7-h3-antibody-drug-conjugate-adc
Summit Therapeutics Announces Clinical Trial Collaboration with GSK to Evaluate Ivonescimab in Combination with GSK’s B7-H3 Antibody Drug Conjugate (ADC)

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Summit Therapeutics Inc.Summit Therapeuticsclinical developmentclinical trialPhase III clinicalpatientsbispecific antibodypotentialsmall cell lung cancerivonescimabcooperative binding