Business
Gain Therapeutics, Inc. Reports Third Quarter 2021 Financial Results and Business Update
Data from Patient-Derived iPSC Study Evaluating STAR Compounds Show Positive Effects on Disease Onset and Progression; Full Data Presented at MJFF’s
About this update from Gain Therapeutics, Inc.
[{"type":"text","content":"Data from Patient-Derived iPSC Study Evaluating STAR Compounds Show Positive Effects on Disease Onset and Progression; Full Data Presented at MJFF’s Parkinson's Disease Therapeutics Conference--- Appoints Matthias Alder as Chief Operating Officer and Appoints 5 Members to Newly Formed Scientific Advisory Board---$40.98 Million in Cash as of September 30, 2021, Provides Runway into Second half of 2023 and a Strong Cash Position to Transition the Company’s Lead Program into Clinical Trials BETHESDA, Md., Nov. 12, 2021 (GLOBE NEWSWIRE) -- Gain Therapeutics, Inc. (Nasdaq: GANX) (“Gain”, or the “Company”), a biotechnology company focused on identifying and optimizing allosteric binding sites that have never been targeted in neurodegenerative diseases and lysosomal storage disorders, today announced its financial results as of and for the third quarter ended September 30, 2021, and highlighted recent corporate accomplishments. “I am very pleased with the progress we have made this quarter on multiple fronts including corporate development, with the appointment of Matthias Alder as COO to several presentations at international symposia and leading medical conferences providing the evidence and data behind our novel programs supporting our transition into clinical trials,” commented Eric Richman, Chief Executive Officer of Gain. “Building on a robust portfolio of data generated to date, the Company will be hosting several presentations to both the investor and medical community that showcase Gains’ supercomputer-powered SEE-Tx™ discovery platform to identify lead STAR compounds for potential treatment of rare genetic and neurodegenerative diseases.” Business and Recent Developments Presented at the Michael J. Fox Foundation (MJFF) Parkinson’s Disease Therapeutics Webinar: Gain presented quantitative data from a patient-derived iPSC study evaluating Structurally Targeted Allosteric Regulator (STAR) compounds as a treatment for Gaucher and Parkinson’s Disease. In cortical and dopaminergic neurons differentiated from patient-derived iPSCs, STAR compounds GT-02287 and GT-02329 displayed: Significant reductions in toxic substrates GluCer and α-synuclein-p129Increase in GCase enzyme activity and GCase protein levelsIncreased trafficking of GCase to the lysosome Study results showed positive effects on key biological read-outs related to disea...