Press release
Fulcrum Therapeutics® to Host Virtual Key Opinion Leader Webcast Featuring Losmapimod for Facioscapulohumeral Muscular Dystrophy (FSHD)
Event to discuss unmet need in FSHD, key measures of disease progression and Phase 3 REACH trial Live webcast March 24, 2022 at 10:00am ET CAMBRIDGE, Mass.,

About this update from Fulcrum Therapeutics, Inc.
[{"type":"text","content":"Event to discuss unmet need in FSHD, key measures of disease progression and Phase 3 REACH trial Live webcast March 24, 2022 at 10:00am ET CAMBRIDGE, Mass., March 17, 2022 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc. (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases, today announced that it will host a Key Opinion Leader (KOL) meeting on Thursday, March 24, 2022 from 10:00am – 12:00pm ET to discuss the company’s program with losmapimod for facioscapulohumeral muscular dystrophy (FSHD). Drs. Nicholas Johnson and Jay Han will join Fulcrum’s senior executives in discussing the unmet need in FSHD, key measures of disease progression, the FSHD landscape and the Phase 3 REACH trial followed by a question-and-answer session. Nicholas E. Johnson, MD, M.Sci., FAAN, is associate professor, division chief of neuromuscular, and vice chair of research in the department of neurology at Virginia Commonwealth University. Jay J. Han, MD, is professor and vice chair residency program director, University of California, Irvine. To register for the live webcast please visit https://ir.fulcrumtx.com/events-and-presentations in the Investor Relations section of the company’s website. Following the live webcast, an archived replay will be available on the website for up to 12 months. About FSHDFSHD is a serious, rare, progressive and debilitating disease for which there are no approved treatments. It is characterized by fat infiltration of skeletal muscle leading to muscular atrophy involving primarily the face, scapula and shoulders, upper arms, and abdomen. Impact on patients includes profound decreases in the ability to perform activities of daily living, loss of upper limb function, loss of mobility and independence and chronic pain. FSHD is one of the most common forms of muscular dystrophy and has an estimated patient population of 16,000 to 38,000 in the United States alone. About LosmapimodLosmapimod is an investigational, selective p38α/β mitogen activated protein kinase (MAPK) inhibitor. Fulcrum exclusively in-licensed losmapimod from GSK following Fulcrum’s discovery of the role of p38α/β inhibitors in the reduction of DUX4 expression and an extensive review of known compounds. Results reported from the ReDUX4 trial demonstrated slowed disease progr...