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Firefly Announces Discovery of New Brain Wave Biomarkers For Differential Diagnosis of ADHD

Over 22 million Americans are diagnosed with ADHD — yet an objective biological marker for distinguishing between its three distinct subtypes has, to date,

articleFirefly Neuroscience, Inc.March 13, 20264/company/firefly-neuroscience-inc/news/firefly-announces-discovery-of-new-brain-wave-biomarkers-for-differential-diagnosis-of-adhd-80
Firefly Announces Discovery of New Brain Wave Biomarkers For Differential Diagnosis of ADHD

About this update from Firefly Neuroscience, Inc.

[{"type":"text","content":"Over 22 million Americans are diagnosed with ADHD — yet an objective biological marker for distinguishing between its three distinct subtypes has, to date, remained elusive1 Firefly’s AI-powered EEG/ERP technology may help identify which ADHD subtype a patient has — potentially complementing subjective symptom checklists with neural signal-based precision Subtype identification could change the clinical equation: Firefly’s platform may help clinicians determine the most appropriate treatment type, inform dosage decisions, and potentially monitor whether an intervention is working The breakthrough advances Firefly’s mission to build the world’s first EEG/ERP brain foundation model — being trained on a growing repository of over 191,000 brain scans KENMORE, N.Y., March 13, 2026 (GLOBE NEWSWIRE) -- Firefly Neuroscience, Inc. (“Firefly” or the “Company”) (NASDAQ: AIFF), an Artificial Intelligence (“AI”) company developing innovative solutions that improve brain health outcomes for patients with neurological and mental disorders, today announced the advancement of research using Resting EEG/Cognitive EEG (ERP) brain scans collected on its FDA-510(k)-cleared Evoke System to potentially distinguish between the three main subtypes of attention-deficit/hyperactivity disorder (“ADHD”): hyperactive and impulsive, inattentive, and combined.2 ADHD represents a U.S. treatment market estimated at over $10 billion, yet the condition has historically been diagnosed without objective biological tools for subtype differentiation.3 Today, a diagnosis of adult ADHD is based upon meeting the following general symptoms-based criteria: symptoms should be present in two or more settings, such as home, work or school; symptoms should clearly interfere with or reduce the functioning of a person in social, work, or school-related activities; symptoms experienced cannot be better explained by another mental health condition, such as depression or anxiety; and symptoms should not only occur during the course of a psychotic disorder like schizophrenia.4 In addition, healthcare professionals typically use the Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) to distinguish between the three types of ADHD. According to the DSM-5, adult ADHD may be diagnosed in the following cases: (i) hyperactive and impulsive type ADHD - at least five symptoms o...

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