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ENZOLYTICS, INC. AND DEPARTMENT OF IMMUNOLOGY, INSTITUTE OF MICROBIOLOGY, BULGARIAN ACADEMY OF SCIENCES BEGINS PROJECT FOCUSING ON DEVELOPMENT OF MELANOMA VACCINE
ENZOLYTICS, INC. AND DEPARTMENT OF IMMUNOLOGY, INSTITUTE OF MICROBIOLOGY, BULGARIAN ACADEMY OF SCIENCES BEGINS PROJECT FOCUSING ON DEVELOPMENT OF MELANOMA VACCINE.
About this update from Enzolytics Inc.
[{"type":"text","content":"Enzolytics, Inc. (OTC PINK: ENZC) (\"enzolytics.com”) (the “Company” or “Enzolytics”) disclosed today the beginning of its second collaborative effort under its three year contract with the Department of Immunology, Institute of Microbiology, Bulgarian Academy of Sciences (the “Academy”). This project will seek to integrate the benefits of the Company’s exclusively licensed lyophilized pepsin with protein-engineered vaccines RtH-GD3P4 or HaH-GD3P4, produced by the Academy for the targeted use of treating melanoma.The Company recently reported on a study conducted at the Ministry of Health National Centre of Infectious and Parasitic Diseases in Sofia, Bulgaria concluding that Chief Science Officer of ENZC and inventor Harry Zhabilov’s patented experimental cancer lyophilized pepsin treatment, is effective in decreasing the growth and spread of cancer cells in breast cancer, colon cancer, prostate cancer, cancer of the larynx, as well as small cell lung cancer. The report prepared by Prof. Genova-Kalu and Prof. Dr. Ivaristova concludes with the statement that “In conclusion, lyophilized pepsin has extremely promising biomedical potential.”Additionally the Academy performed In Vito test on IPF, the active ingredient in the lyophilized pepsin treatment, concluding that a polypeptide complex of lyophilized pepsin, causes cytopathological changes and significantly reduces the survival and/or proliferative activity of the cell cultures used as experimental models. The tested substance exhibits the strongest cytotoxic/cytostatic effect on mammary adenocarcinoma (MCF-7 and MDA-MB-231 lines), cervical carcinoma (HeLa line), colorectal carcinoma (CaCo-2 line) and adenocarcinoma of the prostate (PC-3). A cytotoxic/cytostatic effect was observed on cells from small cell lung cancer (A 549 line) and the line Hep-2 (carcinoma of the larynx). The observed effect was time and concentration dependent, a response that is most likely due to the different biological characteristics of the malignant neoplasms from which the model cell lines were derived, as well as to the phenomenon of heterogeneity of tumor cells.In a separate research report funded by the ‘National Science Fund’, Bulgaria, and ‘National Science Program Young Scientists and Postdoctoral Researchers’, it was demonstrated that the administration of the protein-engineered vaccines RtH-...