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Enveric Biosciences Announces New U.S. Patent for C4-Carboxylic Acid-Substituted Tryptamine Derivatives
New patent provides additional composition of matter and methods of use claims for Enveric’s tryptamine-derived prodrugs including EB-373, a new chemical
About this update from Enveric Biosciences, Inc.
[{"type":"text","content":"\nNew patent provides additional composition of matter and methods of use claims for Enveric’s tryptamine-derived prodrugs including EB-373, a new chemical entity psilocin prodrug\n\n\n CAMBRIDGE, Mass.--(BUSINESS WIRE)--\nEnveric Biosciences (NASDAQ: ENVB) (“Enveric” or the “Company”), a biotechnology company dedicated to the development of novel neuroplastogenic small-molecule therapeutics for the treatment of anxiety, depression, and addiction disorders, today announced that the United States Patent and Trademark Office (USPTO) has issued U.S. Patent No. 11,746,087, titled “C-4 Carboxylic Acid Substituted Tryptamine Derivatives and Methods of Using,” pertaining to the Company’s EVM201 Series and lead candidate EB-373, a psilocin prodrug being developed for the treatment of anxiety disorder.\n\n\nIssued September 5, 2023, the new patent provides Enveric with intellectual property rights for compositions and methods for tryptamine-derived prodrugs utilizing C4 carboxylic acid substituted tryptamine derivatives. This patent complements the recently issued U.S. patent (11,707,447), titled “C4-Carbonothioate-substituted Tryptamine Derivatives and Methods of Using,” providing Enveric with a robust intellectual property portfolio governing psilocin prodrugs designed to potentially elicit a more rapid onset of action, more controlled therapeutic effect, and reduced gastrointestinal side-effects compared to conventional psilocin prodrugs, such as psilocybin. EB-373 was developed from Enveric’s EVM201 Series of molecules, which are rationally designed to achieve altered metabolic and pharmacokinetic properties.\n\n\n“Today’s patent issuance from the USPTO adds another important pillar to Enveric’s intellectual property portfolio as we continue to distinguish our tryptamine-based prodrugs from similar compounds being developed for the treatment of mental health disorders,” said Joseph Tucker, Ph.D., Director and CEO of Enveric. “Both our EVM201 Series, led by EB-373, and our EVM301 Series are designed to capitalize on the potential of neuroplastogens that can enhance neuroplasticity while minimizing unwanted side effects, including prolonged and unpredictable hallucinatory experiences. We expect continued positive IP-related developments in the coming months that, we believe, will serve to further highlight the differentiation and value...