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ENDRA Life Sciences Reports Completion and Top Level Findings of Second Phase of Robarts Research Institute Liver Fat Feasibility Study
New Findings Support Positive, Clinically Useful Correlation to Reference MRI - Feasibility Study Now Complete, Additional Clinical Studies at Other Sites
About this update from Endra Life Sciences Inc.
[{"type":"text","content":"New Findings Support Positive, Clinically Useful Correlation to Reference MRI - Feasibility Study Now Complete, Additional Clinical Studies at Other Sites Expected to be Initiated by Year-End -ANN ARBOR, MI / ACCESSWIRE / September 26, 2019 / ENDRA Life Sciences Inc. (\"ENDRA\") (NASDAQ:NDRA), a pioneer of enhanced ultrasound technologies, today reported that Robarts Research Institute has completed the second phase of the Thermo Acoustic Enhanced Ultrasound (TAEUS) feasibility study of liver fat and, in conjunction with the EASL Nonalcoholic Fatty Liver Disease (NAFLD) Summit in Seville, Spain, ENDRA provided top level findings from the study.A total of 26 volunteer subjects were scanned and rescanned with updated probe architecture and a modified measurement procedure. One subject did not complete the study (no available reference Magnetic Resonance Imaging Proton Density Fat Fraction, or MRI-PDFF), and was excluded. Relative to the first study phase, the 25 subjects scanned in the second phase represented a more broadly distributed population of liver fat, with 15 out of 25 having a clinically relevant liver fat fraction of 5% or greater. Pre-defined TAEUS measurement requirements, related to signal quality and anatomical consistency with conventional ultrasound, excluded seven additional subjects from the final analysis. Eighteen subject data sets were used to determine top line results including correlation with the MRI-PDFF reference measurement, and sensitivity and specificity of the TAEUS measurement to correctly identify subjects with clinically elevated liver fat (≥5% as measured by MRI-PDFF) vs. subjects with healthy levels of liver fat (","length":2214,"tagName":"div"}]