Business
New PointManT DNA enrichment products launched
New PointManT DNA enrichment products launched.
About this update from Ekf Diagnostics Holdings Plc
[{"type":"text","content":"\n \nRNS Number : 0516S EKF Diagnostics Holdings PLC 04 November 2013 \n \n\n \nEKF Diagnostics Holdings plc\n(\"EKF\" or \"the Company\")\n \nNew PointMan™ DNA enrichment products launched\n \nEKF Diagnostics Holdings plc (AIM: EKF), the AIM listed point-of-care diagnostics business, announces that EKF Molecular Diagnostics has launched four new PointMan™ DNA enrichment products for the Research Use Only market, with planned diagnostic registration in Europe in 2014. The new kits are listed below: \n \n\n\n\n\nPointMan™ KRAS codons* 12/13/61 DNA Enrichment Kit\n\n\nthe KRAS gene has proven utility in the treatment of colorectal cancer and the addition of codon 61 may confirm broader genetic variation within the KRAS gene.\n \n\n\n\n\nPointMan™ EGFR DNA Enrichment Kit\n\n\nthe kit includes the addition of the sensitising mutations in exons 19 and 21 which have proven utility for EGFR targeted therapies in non-small cell lung cancer.\n\n\n\n\n\n\n\n\n\n\n\n\nPointMan™ NRAS DNA Enrichment Kit\n\n\nmutations in the NRAS gene are found in approximately 13-25% of all malignant melanomas, occurring frequently in codons 12, 13, and 61.\n \n\n\n\n\nPointMan™ JAK2 DNA Enrichment Kit\n\n\nmutations in the JAK2 gene have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders. \n\n\n\n\n \n* Definition of a codon: 'A sequence of three nucleotides which together form a unit of genetic code in a DNA or RNA molecule.'\n \nThe new launches follow on from the introduction of the first three PointMan™ DNA enrichment products in May 2013, namely BRAF, KRAS and EGFR T790M DNA enrichment kits. The extension of EKF Molecular Diagnostic's portfolio of DNA enrichment kits further enhances the Company's ability to change current DNA extraction and detection practices and address the fast growing companion diagnostics market.\n \nJulian Baines, CEO of EKF commented: \"I'm very pleased to announce the launch of EKF Molecular's latest research kits, adding to our growing portfolio of kits for use in finding companion diagnostics for cancer treatments. I look forward to providing further updates as we steer this business towards commercialisation and launch further research kits that challenge the lack of sensitivi...