Business
Editas Medicine Announces Third Quarter 2020 Results and Update
EDIT-101 for LCA10 ‒ BRILLIANCE trial adult low-dose cohort completed EDIT-301 for sickle cell disease ‒ on track for IND filing by end of 2020 EDIT-201 for

About this update from Editas Medicine, Inc.
[{"type":"text","content":"EDIT-101 for LCA10 ‒ BRILLIANCE trial adult low-dose cohort completed\n EDIT-301 for sickle cell disease ‒ on track for IND filing by end of 2020 EDIT-201 for solid tumors ‒ preclinical data to be presented at SITC and ASH Cash, cash equivalents, and marketable securities of $541 million as of September 30, 2020 CAMBRIDGE, Mass., Nov. 05, 2020 (GLOBE NEWSWIRE) -- Editas Medicine, Inc. (Nasdaq: EDIT), a leading genome editing company, today reported business highlights and financial results for the third quarter of 2020. “We were pleased to regain full operating control of our ocular programs per our new agreement with AbbVie, which provides us with important flexibility. We have finished dosing the first cohort with EDIT-101 in the landmark BRILLIANCE trial and enrollment remains active,” said Cynthia Collins, Chief Executive Officer of Editas Medicine. Ms. Collins continued, “The advancements in our ocular portfolio are complemented by the strategic development of our engineered cell medicines. We are on track to file the IND for EDIT-301 for sickle cell disease in the fourth quarter and are eager to present additional data on this potentially best-in-class medicine and our large-scale manufacturing process at the upcoming American Society of Hematology Annual Meeting. Substantial progress has also been made in the development of EDIT-201, an allogeneic NK cell medicine to treat solid tumors. Preclinical data to be presented at ASH show enhanced tumor killing with EDIT-201 compared to unedited NK cells, and additional data on this program will be featured at the upcoming Society for Immunotherapy of Cancer’s Annual Meeting.” Recent Achievements and Outlook In Vivo CRISPR Medicines EDIT-101 for LCA10BRILLIANCE Phase1/2 adult low-dose cohort completedEditas Medicine (Company) has completed dosing of the first cohort of adult patients with visual light perception only administered the low dose of EDIT-101. Trial enrollment remains active but has experienced a slowdown due to the ongoing impact of the COVID-19 pandemic. Ocular MedicinesRegained full control of ocular medicinesEditas Medicine terminated its 2017 agreement with Allergan, now part of AbbVie, and entered a new agreement with AbbVie that returned development and commercialization rights for ocular medicines to Editas Medicine. As part of the new agreement, AbbVie has tr...