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CytoSorbents Reports New Cardiac Surgery Data with CytoSorb at the European Association for Cardio-Thoracic Surgery (EACTS) Annual Meeting

PRINCETON, N.J., Oct. 12, 2022 /PRNewswire/ -- CytoSorbents Corporation (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in the

articleCytosorbents CorporationOctober 12, 20224/company/cytosorbents-crp/news/cytosorbents-reports-new-cardiac-surgery-data-with-cytosorb-at-the-european-association-for-cardio-thoracic-surgery-eacts-annual-meeting
CytoSorbents Reports New Cardiac Surgery Data with CytoSorb at the European Association for Cardio-Thoracic Surgery (EACTS) Annual Meeting

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[{"type":"text","content":"PRINCETON, N.J., Oct. 12, 2022 /PRNewswire/ -- CytoSorbents Corporation (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery using blood purification via its proprietary polymer adsorption technology, announced the presentation of exciting new data on the use of CytoSorb® in various cardiac surgery indications at the 36th European Association for Cardio-Thoracic Surgery (EACTS) Annual Meeting last week in Milan, Italy. \n\n \n \n \n \n \n \n\n \nDuring the main scientific session, Professor Matthias Thielmann - Dept. of Thoracic and Cardiovascular Surgery, West-German Heart & Vascular Center, University Duisburg-Essen, Germany presented the \"Effect of intraoperative hemoadsorption therapy in acute infective endocarditis with confirmed Staph. aureus bacteremia.\" \nThe incidence of infective endocarditis, or infection of a heart valve, is increasing globally. Staphylococcal aureus endocarditis (SAE) accounts for roughly a quarter to a third of all cases and is a dreaded complication associated with intravenous drug abuse and use of dirty needles, hospital-acquired infections, prosthetic heart valves, and community acquired endocarditis. Importantly, SAE is the most aggressive form of valvular infection and can lead to a myriad of complications including rapid destruction of the valve, heart failure, cytokine storm, florid septic shock, septic embolization, and the highest mortality risk among all types of infective endocarditis, even with surgical replacement of the heart valve. CytoSorb is used in this patient population during open heart surgery to control cytokine storm, reduce inflammation and Staphylococcal toxins, and reverse shock.\nStudy population: 130 consecutive patients with confirmed SAE who underwent heart valve surgery at 2 leading German Heart Centers between 01/2015 – 03/2022. Mean age (60.8 vs. 60.7, p=ns) and baseline risk according to EuroScore II (12.0 vs. 11.9, p=ns) were nearly identical in the two groups. Approximately 25% of patients had a repeat cardiac operation while almost 20% were IV drug users.Study objectives: To compare clinical outcomes between patients who underwent standard of care valve replacement surgery (Control group; n=55) and patients who underwent standard of care valve replacement surgery plus intraoperative hemoadsorp...

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