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Coya Therapeutics Strengthens Scientific Advisory Board (SAB) with the Addition of Neuroimmunology Pioneer, Dr. Guillaume Dorothée, an Expert on the Role of the Immune System and Regulatory T Cells (Tregs) in Alzheimer’s Disease (AD)
Dr. Guillaume Dorothée, Ph.D., is a tenured research director and team head in neuroimmunology at the French National Institute of Health and Medical
About this update from Coya Therapeutics, Inc.
[{"type":"text","content":"\n\nDr. Guillaume Dorothée, Ph.D., is a tenured research director and team head in neuroimmunology at the French National Institute of Health and Medical Research (INSERM) in Paris\n\n\n\nHe is one of the world’s leading experts on the role that the immune system and peripheral-central immune crosstalk play in the pathophysiology of AD\n\n\n\nHis team was the first to illustrate the beneficial role of Regulatory T cells (Tregs) in AD and the therapeutic effects of low dose Interleukin-2 (low dose IL-2) in modifying AD pathology and restoring cognitive function\n\n\n\nDr. Dorothée joins an SAB with leading Treg experts including Dr. Shimon Sakaguchi, the discoverer of Tregs, and the chair of Coya’s SAB, Dr. Stanley Appel, who elucidated the role of Tregs in Amyotrophic Lateral Sclerosis (ALS)\n\n\n\nDr. Dorothée will play an integral role in guiding Coya on its scientific and clinical strategy in AD and other neurodegenerative diseases\n\n\n\n \n\n\n HOUSTON--(BUSINESS WIRE)--\nCoya Therapeutics, Inc. (NASDAQ: COYA) (“Coya” or the “Company”), a clinical-stage biotechnology company developing biologics intended to enhance Treg function, today announced the appointment of Dr. Guillaume Dorothée, Ph.D., to Coya’s SAB, joining a roster of scientific luminaries. Dr. Dorothée will provide insight and perspective into Coya’s clinical programs in ALS and AD, and other indications that Coya is evaluating.\n\n\nDr. Dorothée’s seminal work has focused on the role of the immune system and peripheral-central immune crosstalk in the pathophysiology of AD and other neurodegenerative diseases, with a particular interest in neuroinflammation and its effects on beta Amyloid, Tau, and other AD pathology. He has pioneered research into understanding how Tregs critically control immune responses to Beta Amyloid (Toly-Ndour et al, J Immunol, 2011), and how enhancing Tregs with low dose IL-2 plays a beneficial role in the pathophysiology of AD-like amyloid pathology while restoring cognitive function (Dansokho et al, Brain, 2016).\n\n\n“Coya could not be prouder in having Dr. Dorothée join its SAB. The fact that he discovered the therapeutic role of low dose IL-2 in AD dovetails with Coya’s low dose IL-2 asset, COYA 301, and its highly promising proof of concept clinical data showing cognitive improvement and halting of cognitive decline. He continues ...