Business
Corvus Completes Enrollment in Phase 1 Study of CPI-006 for Patients with COVID-19 and Presents Study Data at 2020 Society for Immunotherapy of Cancer (SITC) Annual Meeting
Data to be presented in a poster and an oral session “Hot Topic Symposium: COVID-19 and Cancer” at SITC Anti-SARS-COV-2 antibody response (IgG and IgM) to
About this update from Corvus Pharmaceuticals, Inc.
[{"type":"text","content":"Data to be presented in a poster and an oral session “Hot Topic Symposium: COVID-19 and Cancer” at SITC\n\n \n \n \n \n \n \n \n \n \n \n \n Anti-SARS-COV-2 antibody response (IgG and IgM) to trimeric spike protein and RBD of SARS-CoV-2. Patients received a 0.3, 1.0 or 3.0 mg/kg single dose of CPI-006 and antibody titers were measured at pre-treatment and at days 28, 56 and 84. Data are shown as box and whisker plot with geometric mean and interquartile ranges. Each dot represents a patient. Also shown are titers from convalescent patients serum obtained 28-42 days after recovery from COVID-19.\n \n \n \n \n \n \n \n \n\n Data shows CPI-006 provided enhanced and prolonged polyclonal humoral immunity to SARS-CoV-2 Plans to initiate pivotal, randomized, double blind trial in December with results expected mid-2021 Hosting R&D Symposium webcast on Thursday, November 12 to highlight COVID-19 program and provide updates on its cancer programs BURLINGAME, Calif., Nov. 09, 2020 (GLOBE NEWSWIRE) -- Corvus Pharmaceuticals, Inc. (NASDAQ: CRVS), a clinical-stage biopharmaceutical company, today announced that it has completed patient enrollment in its Phase 1 study investigating the potential for CPI-006 to provide a novel immunotherapy approach for hospitalized patients with COVID-19. This novel immunotherapy may provide a therapeutic benefit from the activation of a polyclonal antibody response to the SARS-CoV-2 virus and the induction of long term immunity through active immunization. Updated data from the study is being presented this week in a poster presentation and an oral presentation at the 2020 Society for Immunotherapy of Cancer (SITC) Annual Meeting. The oral presentation will take place on Friday, November 13 at 12:15 pm ET as part of Session 301, which is titled “Hot Topic Symposium: COVID-19 and Cancer.” Based on the study data to-date, the Company plans to initiate a pivotal, randomized, double blind study of CPI-006 in hospitalized COVID-19 patients in December with results expected around mid-2021. Lead investigator of the CPI-006 COVID-19 Phase 1 study, Gerard J. Criner, M.D., from Temple University Hospital, said, “The results to-date in the Phase 1 study of CPI-006 for the treatment of COVID-19 have been very encouraging. With relatively low doses of CPI-006, we have seen patients generate high levels of antibodies to ...