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Cognition Therapeutics is Recruiting for Lewy Body Dementia Phase 2 SHIMMER Trial in Seventeen Research Sites Across the U.S.
Estimated Over 1.4 Million Americans Suffer from LBD – Often Misdiagnosed – No Approved Treatments PURCHASE, N.Y., Oct. 12, 2022 (GLOBE NEWSWIRE) -- Lewy Body
About this update from Cognition Therapeutics, Inc.
[{"type":"text","content":"Estimated Over 1.4 Million Americans Suffer from LBD – Often Misdiagnosed – No Approved Treatments\nPURCHASE, N.Y., Oct. 12, 2022 (GLOBE NEWSWIRE) -- Lewy Body Dementia (LBD) patients are actively being recruited by Cognition Therapeutics, Inc. (Nasdaq: CGTX) and its clinical partners for the SHIMMER Phase 2 trial of their CT1812 oral drug therapy at 17 study sites across the country with more expected to open. “The Phase 2 SHIMMER study (NCT05225415) is actively recruiting participants for these sites across the United States, including those that are Lewy Body Dementia Association centers of excellence” added Anthony O. Caggiano, M.D., Ph.D., Cognition’s chief medical officer and head of R&D. “We look forward to working together with our partners to activate the remaining study sites across the country so that patients have local options.” This month is Lewy Body Dementia Awareness month with approximately over 1.4 million people in the United States suffering from the neurodegenerative disease, making it the second most common form of dementia. Often misdiagnosed it also masks itself as Parkinson’s disease and is the largest dementia most have never heard of. \"Patients with LBD can present initially with different symptoms, making it challenging for general practitioners or even neurologists to recognize,” explained James E. Galvin, MD, MPH, the director of the Comprehensive Center for Brain Health at the University of Miami Miller School of Medicine and primary investigator for the SHIMMER study. “In addition, the stigma that exists around mental health can lead patients to under-report neuropsychiatric symptoms, such as hallucinations, which are common in early stages of LBD. This October, during Lewy Body Dementia Awareness Month, let’s recommit to educating ourselves about LBD.” SHIMMER is supported by $30M in grants by the National Institutes of Health’s National Institute on Aging (NIA). The study is a double-blind Phase 2 clinical trial designed to enroll 120 adults between 50 and 80 years of age with a LBD diagnosis, who will be randomized to receive a placebo or one of two daily oral doses of CT1812 for six months. In addition to safety, this study will compare changes in cognitive performance, physical activity, and pharmacokinetic and pharmacodynamic biomarkers to baseline measurements. To learn more about the SHI...