Codexis to Participate in Enzymatic Synthesis Presentations at RNA Leaders Annual Meeting

About this update from Codexis, Inc.

[{"type":"text","content":"REDWOOD CITY, Calif., Aug. 20, 2024 (GLOBE NEWSWIRE) -- Codexis, Inc. (NASDAQ: CDXS), a leading enzyme engineering company, today announced the Company will participate in a presentation and panel discussion at the upcoming RNA Leaders annual meeting, being held September 4-5, 2024, in San Diego, CA. The Company’s presentations will focus on the use of enzymes to drive the scalable and cost-effective manufacture of short inhibitory ribonucleic acid (siRNA) duplexes. During a keynote panel presentation, Stefan Lutz, PhD, Codexis Senior Vice President of Research, in addition to other RNA industry leaders, will discuss how the biopharmaceutical industry is developing new solutions to advance RNA manufacturing, address production capacities and establish new approaches to streamline clinical trials and standardize protocols. The Company’s second presentation will focus on ligation, which enables the joining of siRNA fragments to generate full-length siRNA duplexes. This approach reduces the overall costs of siRNA manufacturing by leveraging the inherent benefits of short fragment synthesis, including higher yield and increased purity. Codexis recently launched its double-stranded RNA ligase screening and optimization services, and the Company’s presentation will demonstrate improvements across key ligase attributes critical for siRNA manufacturing utilizing its Enzyme Catalyzed Oligonucleotide (ECO) Synthesis™ manufacturing platform. These include high catalytic activity at high substrate loading, as well as improved performance on challenging sequences and modification near ligation junctions. Additionally, improvements in manufacturability of double-stranded RNA ligases are expected to result in a more reliable and scalable enzyme supply. Attendees of the conference may visit with the Codexis team at Booth #9 in the exhibition hall. Appointments may be made in advance by clicking here. Presentation Details Keynote Panel: Scaling RNA Therapies to Deliver on the Promise of Precision MedicineDate: Wednesday, September 4, 2024Time: 10:15 – 10:55 am Pacific Daylight Time (PDT)Location: San Diego Convention Center, San Diego, CACodexis Speaker: Stefan Lutz, PhD, Senior Vice President of Research Presentation Title: Cost-effective Manufacturing of siRNA Duplexes at High Yield and Purity Using Engineered Double-stranded RNA LigasesDate: ...

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