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Codexis Documentary Showcases its Specialized Capabilities Engineering High Performance Enzymes to Enable Delivery of Novel Therapeutics
New Film Highlights Company Commitment to Transforming RNAi Therapeutics Landscape REDWOOD CITY, Calif., July 31, 2023 (GLOBE NEWSWIRE) -- Codexis, Inc.

About this update from Codexis, Inc.
[{"type":"text","content":"New Film Highlights Company Commitment to Transforming RNAi Therapeutics Landscape\nREDWOOD CITY, Calif., July 31, 2023 (GLOBE NEWSWIRE) -- Codexis, Inc. (NASDAQ: CDXS), a leading enzyme engineering company, today announced the launch of a new mini documentary as part of an ongoing campaign in support of World Health Day. The film showcases the Company’s recently unveiled Enzyme-Catalyzed Oligonucleotide (ECO) Synthesis™ technology, a propriety new synthesis platform that is being developed to enable the manufacture of ribonucleic acid interference (RNAi) therapeutics at scale and built around Codexis’ world-leading CodeEvolver® technology. “Codexis is at a unique inflection point in its 20-year history. Building upon our existing strength in enzyme engineering, we believe that we have identified a series of high-impact programs where our enzymes and expertise can drive meaningful differences for our customers, and ultimately patients,” said Stephen Dilly, MBBS, PhD, President and Chief Executive Officer of Codexis. “Our ECO Synthesis™ technology provides us the potential to create significant value across the healthcare landscape by enabling large-scale manufacture of RNAi therapeutics, an exploding class of medicines being developed to address significant diseases, such as cardiovascular disease, Alzheimer’s disease and cancer. If we are successful, Codexis will enable the commercial-scale production of RNAi therapeutics, potentially impacting hundreds of millions of patients on a global scale.” Codexis’ ECO Synthesis™ technology is a proprietary new synthesis platform that is being developed to support the manufacture of RNAi therapeutics by efficiently synthesizing short inhibitory RNA (siRNA) oligonucleotide sequences. By replacing conventional chemical processes with enzymatic methods, ECO Synthesis™ technology is designed to address the scalability limitations and high volumes of hazardous waste historically associated with oligonucleotide manufacturing. The Company plans to demonstrate gram-scale synthesis of its ECO Synthesis™ technology by the end of 2023, which will enable pre-commercial testing with select customers in 2024 before its planned commercial launch. The ECO Synthesis™ technology platform is where Codexis’ core technical competency and existing commercial infrastructure come together, positioning the Compa...