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Cocrystal Pharma Presents Positive Data from U.S. Phase 2a Study of CC-31244 Demonstrating Ability to Identify Patients More Likely to Respond to Ultrashort Treatment of HCV
- New data presented at the American Association for the Study of Liver Diseases (AASLD) 2019 Liver Meeting - - Patients that achieved SVR had significantly
About this update from Cocrystal Pharma, Inc.
[{"type":"text","content":"- New data presented at the American Association for the Study of Liver Diseases (AASLD) 2019 Liver Meeting - \n - Patients that achieved SVR had significantly higher frequencies of terminally differentiated effector memory CD8+ T cells compared with those who relapsed - - Development of ultrashort treatment for hepatitis C virus (HCV) consists of CC-31244, an oral, potent, broad-spectrum NNI, as a part of combination therapy to include approved HCV DAAs (direct antiviral agents) - BOTHELL, WA, Nov. 11, 2019 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), (“Cocrystal” or the “Company”), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, presented at the AASLD 2019 Liver Meeting being held November 8-12, 2019 in Boston, MA, new data in a poster demonstrating positive data from its triple regimen, U.S. Phase 2a study evaluating CC-31244 and sofosbuvir/velpatasvir (Epclusa) for the ultrashort treatment of HCV infected individuals. The poster titled, “Immune Cell Phenotypes Associated with Successful Response to 2 Weeks of a Novel Non-Nucleoside Inhibitor CDI-31244 Concurrent with 6 Weeks of Sofosbuvir/Velpatasvir in Subjects with Chronic Hepatitis C Genotype 1 Infection,” was presented by Joel Chua, MD, Assistant Professor of Medicine of the Institute of Human Virology at the University of Maryland School of Medicine and Principal Investigator of the U.S. Phase 2a trial, on Sunday November 10, 2019 and is available on the Company’s website here. “We are pleased with the new data from the U.S. Phase 2a study that were presented this past weekend at the AASLD 2019 Liver Meeting. By investigating the association of specific immune cell biomarkers with sustained virologic response (SVR) or relapse in 12 treatment-native patients with chronic HCV genotype 1 infection without cirrhosis, we were able to successfully identify patients that are more likely to respond to our shorter treatment regimen,” commented Dr. Sam Lee, President of Cocrystal. “With the data demonstrated to date, we believe that CC-31244 has the potential to address the areas of unmet need that still exist in the HCV treatment landscape including the high cost which acts as a major barrier for treatment. We are grateful to Dr. Chua and his team and look forward to advancing the development of CC-31244 and its poten...