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CNS Pharmaceuticals To Release Interim Data By The End Of The Year For Potential Glioblastoma Drug Candidate
HOUSTON, TX / ACCESSWIRE / November 16, 2023 / Glioblastoma is a highly aggressive type of brain cancer with no cure, leading to a grim prognosis and average
About this update from Cns Pharmaceuticals, Inc.
[{"type":"text","content":"HOUSTON, TX / ACCESSWIRE / November 16, 2023 / Glioblastoma is a highly aggressive type of brain cancer with no cure, leading to a grim prognosis and average survival time of only 14 to 16 months. With no approved treatment for recurrent GBM anywhere in the world, it is considered one of the greatest unmet needs in oncology. GBM is so difficult to treat partly because the greatest challenge for new neuro-oncology therapies is simply gaining access to the brain, which the body treats as its most protected organ within what's called the blood brain barrier. The blood brain barrier is a highly specialized network of cells that both actively and passively protect the brain and maintain the brain's microenvironment. One of its primary functions is limiting toxins from entering the brain. This is a key reason why current chemotherapies are ineffective against GBM; they are not even able to reach the tumor.Furthermore, the breakthroughs in immuno-oncology such as checkpoint inhibitors and vaccines that have delivered tremendous results in other cancers have largely missed the mark against GBM. Trial after large trial in the last ten years has failed to show efficacy - this inefficiency is thought to occur because the GBM tumors themselves are immunologically null.CNS Pharmaceuticals Set To Release Data On GBM Drug CandidateCNS Pharmaceuticals (NASDAQ:CNSP) is a biopharmaceutical company focused on developing innovative therapies for central nervous system disorders, specifically aggressive brain cancers. One of their leading treatment candidates is Berubicin, a chemotherapy drug that interferes with the DNA of cancer cells to inhibit their growth and potentially shrink tumors. Berubicin is an anthracycline, a clinically trusted class of drugs in use for 60 years against dozens of common cancers. However, unlike all other anthracyclines and other traditional chemotherapy drugs, CNS Pharmaceuticals reports that Berubicin has the ability to penetrate the blood-brain barrier and directly target cancer cells in the brain, increasing its potential effectiveness.CNS Pharmaceuticals has received FDA Orphan Drug Designation and Fast Track Designation, which together grant them exclusive marketing rights and expedited development and review of drugs for serious conditions. The company is conducting a potentially pivotal clinical trial designed t...